Results 41 to 50 of about 453,581 (148)

Eph/ephrin Function Contributes to the Patterning of Spinocerebellar Mossy Fibers Into Parasagittal Zones

Frontiers in Systems Neuroscience, 2020
Purkinje cell microcircuits perform diverse functions using widespread inputs from the brain and spinal cord. The formation of these functional circuits depends on developmental programs and molecular pathways that organize mossy fiber afferents from ...
Elizabeth P. Lackey, Elizabeth P. Lackey, Elizabeth P. Lackey, Roy V. Sillitoe, Roy V. Sillitoe, Roy V. Sillitoe, Roy V. Sillitoe, Roy V. Sillitoe   +7 more
doaj   +1 more source

Humanization for neurological disease modeling: A roadmap to increase the potential of Drosophila model systems

Animal Models and Experimental Medicine, 2023
Neuroscience and neurology research is dominated by experimentation with rodents. Around 75% of neurology disease‐associated genes have orthologs in Drosophila melanogaster, the fruit fly amenable to complex neurological and behavioral investigations ...
Vladimir L. Katanaev
doaj   +1 more source

Preclinical and experimental evidence of salvianolic acid B in the treatment of neurological diseases

Frontiers in Pharmacology
BackgroundNeurological diseases such as stroke and Alzheimer’s disease pose increasing challenges to global public health. Salvianolic Acid B (SalB), a major active component of Salvia miltiorrhiza, has garnered attention due to its anti-inflammatory ...
Shijun Bi, Shibing Liu, Kunyuan Zhu, Dandan Gao, Ligang Chen, Chunyong Yu, Guobiao Liang   +6 more
doaj   +1 more source

Stem cell transplantation in neurological diseases: improving effectiveness in animal models.

Frontiers in Cell and Developmental Biology, 2014
Neurological diseases afflict a growing proportion of the human population. There are two reasons for this: first, the average age of the population (especially in the industrialised world) is increasing, and second, the diagnostic tools to detect these ...
Raffaella eAdami, Giuseppe eScesa, Daniele eBottai   +2 more
doaj   +1 more source

Thalamic deep brain stimulation improves movement in a cerebellar model of lesion-based status dystonicus

Neurotherapeutics
Dystonia is the third most common movement disorder and an incapacitating co-morbidity in a variety of neurologic conditions. Dystonia can be caused by genetic, degenerative, idiopathic, and acquired etiologies, which are hypothesized to converge on a ...
Megan X. Nguyen, Amanda M. Brown, Tao Lin, Roy V. Sillitoe, Jason S. Gill   +4 more
doaj   +1 more source

Investigating the Unmet Need and Future of Neurorehabilitation in India: A Scoping Review [PDF]

Iranian Rehabilitation Journal
Objectives: This study explores the challenges of implementing physical rehabilitation for people with neurological diseases at in-hospital and community levels in India, summarizes the unmet needs of evidence-based physical neurorehabilitation in India,
Dorcas B C Gandhi, Ivy A Sebastian, Amreen Mahmood, Pradeepa Nayak, Mridul Makkar, Dimple Dawar, Nistara S Chawla, Jeyaraj Durai Pandian   +7 more
doaj  

Modeling the Neurologic and Cognitive Effects of Hyponatremia [PDF]

Journal of the American Society of Nephrology, 2016
Acute hyponatremia causes swelling of brain cells and, if of a sufficient degree, increased intracranial pressure. This is a consequence of the relative impermeability of the blood-brain barrier to sodium ions[1][1]; this principle underlies the clinical utility of hypertonic NaCl infusion in ...
openaire   +3 more sources

Modeling of age-related neurological disease: utility of zebrafish

Frontiers in Aging Neuroscience
Many age-related neurological diseases still lack effective treatments, making their understanding a critical and urgent issue in the globally aging society.
Tohgo Kanoh, Takamasa Mizoguchi, Ayako Tonoki, Motoyuki Itoh, Motoyuki Itoh, Motoyuki Itoh   +5 more
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Neurological manifestations of encephalitic alphaviruses, traumatic brain injuries, and organophosphorus nerve agent exposure

Frontiers in Neuroscience
Encephalitic alphaviruses (EEVs), Traumatic Brain Injuries (TBI), and organophosphorus nerve agents (NAs) are three diverse biological, physical, and chemical injuries that can lead to long-term neurological deficits in humans.
Morgen VanderGiessen, Morgen VanderGiessen, Caroline de Jager, Julia Leighton, Hehuang Xie, Michelle Theus, Erik Johnson, Kylene Kehn-Hall, Kylene Kehn-Hall   +8 more
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Data-driven analyses of motor impairments in animal models of neurological disorders.

PLoS Biology, 2019
Behavior provides important insights into neuronal processes. For example, analysis of reaching movements can give a reliable indication of the degree of impairment in neurological disorders such as stroke, Parkinson disease, or Huntington disease.
Hardeep Ryait, Edgar Bermudez-Contreras, Matthew Harvey, Jamshid Faraji, Behroo Mirza Agha, Andrea Gomez-Palacio Schjetnan, Aaron Gruber, Jon Doan, Majid Mohajerani, Gerlinde A S Metz, Ian Q Whishaw, Artur Luczak   +11 more
doaj   +1 more source