Phase 1/2 randomized, observer-blind clinical trial of a first-generation, mRNA-based vaccine against seasonal influenza and COVID-19 in healthy adults [PDF]
Human Vaccines & ImmunotherapeuticsA multicomponent vaccine against seasonal influenza and COVID-19 could reduce disease burden in adults by providing simultaneous protection in a single-dose regimen.
Amanda K. Rudman Spergel +22 more
doaj +2 more sources
Immunostimulatory and Immunodynamic Modeling Analysis to Determine a Plausible Starting Dose of mRNA‐4359 for Use in First‐In‐Human Trials [PDF]
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.ABSTRACT The investigational antigen‐specific immunotherapy mRNA‐4359 is a lipid nanoparticle–encapsulated mRNA‐based immunotherapy that encodes for the immunogenic indoleamine 2,3‐dioxygenase (IDO) and programmed death‐ligand 1 (PD‐L1) antigens.
Stephen A. Greene +7 more
wiley +2 more sources
Health disparities in chronic liver disease
Hepatology, EarlyView., 2022 Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian +3 more
wiley +1 more source
La crisis no moderna de la universidad moderna [PDF]
, 1997 [La crisis no moderna de la universidad moderna]William Thayer.Editorial Cuarto Propio,Santiago, 1996,239 ...
Oyarzún, Pablo
core +2 more sources
Narratives of Modern Architecture: learning at the intersection of cross-historical constructions [PDF]
, 2016 This paper presents the results of experimental course work in 2015 with secondyear students at IE School of Architecture and Design under the auspices of Culture and Theory in Architecture I.
Vela Castillo, José
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A novel mechanism for the loss of mRNA activity in lipid nanoparticle delivery systems
Nature Communications, 2021 Lipid nanoparticle delivery of mRNA vaccines has become of particular importance, however, mRNA stability is a major concern. Here, the authors report on a study of lipid impurity mRNA interactions using reverse phase ion pair HPLC to identify reactions ...
Meredith Packer +4 more
doaj +1 more source
Human Vaccines & Immunotherapeutics, 2021 Respiratory Syncytial Virus (RSV) causes lower respiratory tract infections that can be severe and sometimes fatal. The risk for severe RSV infection is highest in infants and older adults.
Antonios O. Aliprantis +17 more
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A comprehensive review of SARS-CoV-2 vaccines: Pfizer, Moderna & Johnson & Johnson
Human Vaccines & Immunotherapeutics, 2022 The novel coronavirus outbreak was declared a pandemic in March 2020. We are reviewing the COVID-19 vaccines authorized for use in the United States by discussing the mechanisms of action, administration, side effects, and efficacy of vaccines developed ...
Rikin Patel +4 more
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Lluís Font, Pere (2016). Cristianisme i modernitat: Per una inculturació moderna del cristianisme [PDF]
, 2017 Lluís Font, Pere (2016)Cristianisme i modernitat: Per una inculturació moderna del cristianismeBarcelona: Fundació Joan Maragall / Editorial Cruïlla, 347 p.ISBN 978-84-661-4028-7Lluís Font, Pere (2016)Cristianisme i modernitat: Per una inculturació ...
Mensa Valls, Jaume
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Geografias Moderna e Pós-Modernas
GEOgraphia, 2009 Resumo Instituído e sucessivamente recriado no âmbito da modernidade, o discurso geográfico vê-se já de um tempo desafiado pelas críticas e referências do pós-moderno. Sobretudo em face de as mudanças recentes envolvendo a geografia humanista e a geografia crítica terem passado ao largo do avanço ...
openaire +2 more sources