Results 91 to 100 of about 956,533 (304)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

APLIKASI FILM EDIBEL DAN KEMASAN ATMOSFIR TERMODIFIKASI UNTUK MENINGKATKAN UMUR SIMPAN BUAH SALAK TEROLAH MINIMAL

open access: yesJurnal Ilmu Pertanian Indonesia, 2010
Snake fruit is an exotic fruit from Indonesia, and nowadays has increasing in demand. There is opportunity to market minimally processed snake fruit, but this product becomes very highly perishable because of increasing in respiration rate.
Usman Ahmad   +2 more
doaj  

Salted and dried Cod preserved by vacuum and modified atmosphere

open access: yesFrontiers in Marine Science, 2014
Temperatures higher than 20ºC can boost the growth, on the salted and dried cod surface, of bacteria that present a red pigment (Rodrigues et al., 2003; Rodrigues et al., 2005).
Maria José Rodrigues
doaj   +1 more source

A coherent optical link through the turbulent atmosphere

open access: yes, 2010
We describe the realization of a 5 km free space coherent optical link through the turbulent atmosphere between a telescope and a ground target. We present the phase noise of the link, limited mainly by atmospheric turbulence and mechanical vibrations of
André Clairon   +13 more
core   +3 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Aplicações de tecnologias pós-colheita para bananas 'Prata-Anã' produzidas em Roraima Application of postharvest technologies for bananas 'Prata-Anã' produced and marketed in the Roraima - Brazil

open access: yesRevista Brasileira de Engenharia Agrícola e Ambiental, 2012
Neste trabalho objetivou-se manter a qualidade e aumentar o tempo de prateleira durante a pós-colheita de bananas 'Prata-Anã' e se avaliou a eficiência do armazenamento refrigerado (AR) e da atmosfera modificada (AM) pelo uso de embalagens plásticas de ...
Marcos A. de S. Prill   +5 more
doaj   +1 more source

The proper motion and energy distribution of the isolated neutron star RX J0720.4-3125

open access: yes, 2003
ESO 4m class telescope and VLT deep imaging of the isolated neutron star RX J0720.4-3125 reveals a proper motion of mu = 97 +/-12 mas/yr and a blue U-B color index.
Biggs   +31 more
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Modeling the Effect of Modified Atmospheres on Conidial Germination of Fungi from Dairy Foods

open access: yesFrontiers in Microbiology, 2017
Modified atmosphere packaging (MAP) is commonly applied to extend food shelf-life. Despite growth of a wide variety of fungal contaminants has been previously studied in relation to modified-atmospheres, few studies aimed at quantifying the effects of ...
Nicolas Nguyen Van Long   +6 more
doaj   +1 more source

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