Results 71 to 80 of about 2,367,195 (295)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Quality of beans stored under hermetic conditions Qualidade de feijão armazenado em condições herméticas

Engenharia Agrícola, 2011
This study aimed to evaluate the quality of beans (Phaseolus vulgaris L.) stored with different moisture contents under hermetic conditions. Beans with 12.3%, 15.7%, and 17.8% moisture content were used in the experiment.
Romenique da S Freitas, Lêda R. DA Faroni, Adalberto H Sousa, Paulo R Cecon, Marcela S Carvalho   +4 more
doaj   +1 more source

Perforated modified atmosphere packaging to extend retail shelf life of blueberries and raspberries

Blueberries and raspberries are highly perishable fruit for which storability and marketability are limited by fungal decay and rapid quality deterioration.
Wilson, M.D., Stanley, R.A., Huynh, N.K.
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Physicochemical Changes and Antioxidant Metabolism of Actinidia arguta Fruit (Kiwiberry) Under Various Cold-Storage Conditions

Molecules
Actinidia arguta (kiwiberry) is a fruit with significant health benefits, and research continues to identify factors that enhance its storability while maintaining quality.
Barbara Łata, Rafał Wołosiak, Ewa Majewska, Beata Drużyńska, Małgorzata Piecyk, Katarzyna Najman, Anna Sadowska, Piotr Latocha   +7 more
doaj   +1 more source

Armazenamento refrigerado sob atmosfera modificada de pedúnculos de cajueiro-anão-precoce dos clones CCP-76, end-157, end-183 e end-189 Storage of cashew apples from dwarf clones CCP-76, end-157, end-183 and end-189 under refrigeration and modified atmosphere

Revista Brasileira de Fruticultura, 2002
Pedúnculos de clones de cajueiro-anão-precoce, dos clones CCP-76, END-157, END-183 e END-189, foram armazenados durante 25 dias, sob refrigeração associada a atmosfera modificada, com o objetivo de avaliar o efeito das condições atualmente utilizadas (5 ...
Auricélia de Souza Morais, Geraldo Arraes Maia, Raimundo Wilane de Figueiredo, Ricardo Elesbão Alves, Heloísa Almeida Cunha Filgueiras, Carlos Farley Herbster Moura   +5 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Potassium permanganate effects in postharvest conservation of the papaya cultivar Sunrise Golden Permanganato de potássio na conservação pós-colheita da cultivar de mamão Sunrise Golden

Pesquisa Agropecuária Brasileira, 2009
The objective of this work was to evaluate the effects of KMnO4 on the extension of postharvest life of 'Sunrise Golden' papaya, stored under modified atmosphere and refrigeration.
Danieele Fabíola Pereira Silva, Luiz Carlos Chamhum Salomão, Dalmo Lopes de Siqueira, Paulo Roberto Cecon, Aline Rocha   +4 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Utilização de diferentes embalagens plásticas para a conservação de produto minimamente processado de mangas 'Tommy Atkins' Different plastic packing for product conservation of mangoes 'Tommy Atkins' minimally processed

Revista Brasileira de Fruticultura, 2009
O trabalho objetivou a avaliação do potencial de conservação de mangas 'Tommy Atkins', minimamente processadas, utilizando-se de diferentes tipos de embalagens plásticas para o estabelecimento da atmosfera modificada (AM) passiva.
Leandro Camargo Neves, Vanuza Xavier da Silva, Luciléia Rodrigues Ferraz, Marcos André de Souza Prill, Sergio Ruffo Roberto   +4 more
doaj   +1 more source