Results 101 to 110 of about 2,950,352 (332)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

The Blazhko behaviour of RR Geminorum II -- long-term photometric results

, 2007
Context. RR Gem is one of the few Blazhko RR Lyrae that has photometric observations available extended enough to study the long-term courses of its pulsation and modulation properties in detail. Aims.
Alania, B. Szeidl, Balázs-Detre, Balázs-Detre, Batyrev, Batyrev, Blazhko, Braune, Chadid, Chadid, Chudovichev, Detre, Dubiago, Dziembowski, Epstein, Fitch, Graff, Ivanov, J. Jurcsik, Jurcsik, Jurcsik, Jurcsik, Jurcsik, Kanishcheva, Kleissen, Kolenberg, Kovács, LaCluyzé, Lange, Lange, Lange, Liu, Luizet, Mandel, Nagy, Preston, Smith, Smith, Stepien, Sódor, Waterfield, Wils, Á. Sódor   +42 more
core   +1 more source

Sirtuin Modulators [PDF]

, 2011
Members of the sirtuin family including the founding protein Sir2 in Saccharomyces cerevisiae have been linked to lifespan extension in simple organisms. This finding prompted evaluation of the role of Sir2 orthologues in many aging-associated conditions including neurodegeneration, type II diabetes and cancer.
Sumit S, Mahajan, Vid, Leko, Julian A, Simon, Antonio, Bedalov   +3 more
openaire   +2 more sources

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Modulation in English Into Indonesia Translation [PDF]

, 2014
This descriptive-qualitative research investigated the modulation phenomena and measured the accuracy level of the phenomena occurring in the translated text.
Misbah, H. (Hasanul)
core  

Limitation of the modulation method to smooth wire guide roughness

, 2010
It was recently demonstrated that wire guide roughness can be suppressed by modulating the wire currents so that the atoms experience a time-averaged potential without roughness. We theoretically study the limitations of this technique. At low modulation
C. L. Garrido Alzar, E. Landau, I. Bouchoule, J.-B. Trebbia, R. Folman   +4 more
core   +1 more source

Phenolic Compounds Impact on Rheumatoid Arthritis, Inflammatory Bowel Disease and Microbiota Modulation [PDF]

, 2021
Rosa Direito, João Rocha, Bruno Sepodes, Maria Eduardo Figueira   +3 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Nonlinear PDEs with modulated dispersion I: Nonlinear Schr\"odinger equations [PDF]

, 2015
We start a study of various nonlinear PDEs under the effect of a modulation in time of the dispersive term. In particular in this paper we consider the modulated non-linear Schr\"odinger equation (NLS) in dimension 1 and 2 and the derivative NLS in ...
Chouk, K., Gubinelli, M.
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source