Results 61 to 70 of about 2,300,015 (251)
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
FEBS Letters, EarlyView.Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner +7 more
wiley +1 more source
Letters in Mathematical Physics, 2009 Developing the ideas of Bressler and Soibelman and of Karabegov, we introduce a notion of an oscillatory module on a symplectic manifold which is a sheaf of modules over the sheaf of deformation quantization algebras with an additional structure. We compare the category of oscillatory modules on a torus to the Fukaya category as computed by Polishchuk ...
openaire +3 more sources
Three-Dimensional EXIT Chart Analysis of Iterative Detection Aided Coded Modulation Schemes
, 2006 The iterative convergence of iteratively detected coded modulation schemes having different block lengths, decoding complexity and an unequal error protection capability is studied, when communicating over AWGNchannels using 8PSK modulation.
Hanzo, L., Ng, S.X., Tee, R.Y.S.
core
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Feed-forward Space Vector Modulation for Single-Phase Multilevel Cascade Converters with any DC voltage ratio [PDF]
, 2009 Modulation techniques for multilevel converters can create distorted output voltages and currents if the DC link voltages are unbalanced. This situation can be avoided if the instantaneous DC voltage error is not taken into account in the modulation ...
Carrasco Solís, Juan Manuel +5 more
core
The Konkoly Blazhko Survey: Is light-curve modulation a common property of RRab stars?
, 2009 A systematic survey to establish the true incidence rate of the Blazhko modulation among short-period, fundamental-mode, Galactic field RR Lyrae stars has been accomplished. The Konkoly Blazhko Survey (KBS) was initiated in 2004. Since then more than 750
Alard +58 more
core +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
, 2000 We describe the acoustic-prosodic and syntactic-prosodic annotation and classification of boundaries, accents and sentence mood integrated in the Verbmobil system for the three languages German, English, and Japanese. For the acoustic-prosodic classification, a large feature vector with normalized prosodic features is used.
Zeißler, Viktor +6 more
openaire +3 more sources