Results 61 to 70 of about 5,665,898 (300)

Molecular classification and outcomes in pediatric aplastic anemia with myeloid neoplasm-associated gene variants

Frontiers in Pediatrics
BackgroundThe genetic variations in aplastic anemia (AA) patients are closely related to clonal hematopoiesis, but there is limited research on this topic in children with AA.
Danni Li, Meiling Liao, Yuye Liu, Luying Zhang, Yingxue Hong, Yuxia Guo, Xianmin Guan, Ying Dou, Xianhao Wen   +8 more
doaj   +1 more source

The role of neutrophil extracellular traps in ulcerative colitis [PDF]

Yixue xinzhi zazhi
Objective To investigate the role of neutrophil extracellular traps (NETs) in the pathogenesis of ulcerative colitis (UC).Methods RNA data from UC patients and normal controls were downloaded from the GEO database to screen for differential expression ...
MENG Qiuyue, YUAN Yifan, LI Na, LU Jiali, YE Mei   +4 more
doaj   +1 more source

Relevance of ARID1A Mutations in Endometrial Carcinomas

Diagnostics, 2022
Since the Cancer Genome Atlas (TCGA) project identified four distinct groups based on molecular alterations, mutation analyses have been integrated into the characterization of endometrial carcinomas (ECs). ARID1A seems to be the subunit more involved in
Antonio De Leo, Gloria Ravegnini, Francesco Musiani, Thais Maloberti, Michela Visani, Viviana Sanza, Sabrina Angelini, Anna Myriam Perrone, Pierandrea De Iaco, Angelo Gianluca Corradini, Francesca Rosini, Marco Grillini, Donatella Santini, Claudio Ceccarelli, Claudio Zamagni, Giovanni Tallini, Dario de Biase   +16 more
doaj   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Molecular classification of hepatocellular carcinoma [PDF]

Digestive and Liver Disease, 2010
Hepatocellular carcinoma (HCC) is the most frequent tumour derived from the malignant transformation of hepatocytes. It is well established that cancer is a disease of the genome and, as in other types of solid tumours, a large number of genetic and epigenetic alterations are accumulated during the hepatocarcinogenesis process.
openaire   +4 more sources

MRI as an assessment tool for prognostic risk stratification of endometrial carcinoma patients based on molecular classification

Journal of Obstetrics and Gynaecology
Background Non-invasive risk stratification for patients with endometrial carcinoma (EC) is important for developing personalised treatment plans. Our study aimed to explore the ability of quantitative MRI parameters to predict the risk stratification of
Tingting Cui, Ying Gao, Bei Gu, Jinsong Guo, Yunlong Yue   +4 more
doaj   +1 more source

Molecular Classification Using Hyperdimensional Graph Classification

2024 International Joint Conference on Neural Networks (IJCNN)
Our work introduces an innovative approach to graph learning by leveraging Hyperdimensional Computing. Graphs serve as a widely embraced method for conveying information, and their utilization in learning has gained significant attention. This is notable in the field of chemoinformatics, where learning from graph representations plays a pivotal role ...
Pere Vergés, Igor Nunes, Mike Heddes, Tony Givargis, Alexandru Nicolau   +4 more
openaire   +4 more sources

Comprehensive characterization of extracellular matrix-related genes in PAAD identified a novel prognostic panel related to clinical outcomes and immune microenvironment: A silico analysis with in vivo and vitro validation

Frontiers in Immunology, 2022
The extracellular matrix (ECM) is a vital component of the tumor microenvironment, which interplays with stromal and tumor cells to stimulate the capacity of cancer cells to proliferate, migrate, invade, and undergo angiogenesis.
Xu Chen, Xu Chen, Qihang Yuan, Jifeng Liu, Shilin Xia, Shilin Xia, Shilin Xia, Xueying Shi, Xueying Shi, Yuxin Su, Zhizhou Wang, Zhizhou Wang, Shuang Li, Shuang Li, Shuang Li, Dong Shang, Dong Shang, Dong Shang   +17 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Molecular Classification of Gastric Adenocarcinoma

Gastroenterology Research, 2019
As one of the leading causes of cancer-related deaths, gastric cancer (GC) has gained more and more attention. Although most GCs are adenocarcinomas, they have considerable heterogeneity among patients. Thus, appropriate classification and individualized treatment of GCs is essential.
Wang, Qianqian, Liu, Ganglei, Hu, Chunhong   +2 more
openaire   +3 more sources