Results 161 to 170 of about 3,038,058 (339)

Molecular Identification of <i>Campylobacter</i> Species Isolated from Patients with Gastroenteritis in Edirne, Turkey

, 2022
Canan Eryıldız, Nermin Şakru, Kıymet Tabakçioğlu, Mediha Uğur, Şebnem Bukavaz   +4 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Performance of a self-developed panel for biogeographic ancestry inference and dissection of the genetic background of three Tibetan groups

Hereditas
Background In this study, we used a panel consisting of 56 autosomal ancestry-informative insertion/deletions (AIM-InDels) for biogeographic ancestry inference, three Y-InDels, and one Amelogenin gene, and verified its performance in Gannan Tibetan ...
Yifeng Lin, Xi Yuan, Xi Wang, Shuanglin Li, Hongbin Yao, Bonan Dong, Bofeng Zhu   +6 more
doaj   +1 more source

Molecular Identification of d-Ribulokinase in Budding Yeast and Mammals

, 2016
Charandeep Singh, Enrico Glaab, Carole L. Linster   +2 more
openalex   +1 more source

Nine Human Sparganosis Cases in Thailand with Molecular Identification of Causative Parasite Species [PDF]

, 2014
Adhiratha Boonyasiri, Pornsuk Cheunsuchon, Yupin Suputtamongkol, Hiroshi Yamasaki, Oranuch Sanpool, Wanchai Maleewong, Pewpan M. Intapan   +6 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

MOLECULAR IDENTIFICATION OF TWO SIBLING SPECIES UNDER THE NAME GRACILARIA CHILENSIS (RHODOPHYTA, GRACILARIALES)^1,3 [PDF]

, 2004
Séverine Cohen, Sylvain Faugeron, Emilio A. Martı́nez, Juan A. Correa, Frédérique Viard, Christophe Destombe, Myriam Valéro   +6 more
openalex   +1 more source

Peer Review #3 of "Identification and molecular characterization of mutations in nucleocapsid phosphoprotein of SARS-CoV-2 (v0.1)"

, 2021
Gajendra Kumar, Azad Corresp, Gajendra Kumar Azad, Gajendra Kumar Azad, S Ahmed, A Quadeer, M Mckay, I Astuti, Ysrafil, G Azad, D Blanco-Melo, B Nilsson-Payant, W Liu, S Uhl, D Hoagland, R Mller, T Jordan, K Oishi, M Panis, D Sachs, T Wang, R Schwartz, J Lim, R Albrecht, Br, G Chand, A Banerjee, G Azad, G Chand, A Banerjee, G Azad, C Chang, M Hou, C Chang, C Hsiao, T Huang, N Chen, M Zhou, X Dong, J Qu, F Gong, Y Han, Y Qiu, J Wang, Y Liu, Y Wei, J Xia, T Yu, X Zhang, L Zhang, S Chenavas, T Cre in, B Delmas, Rwh Ruigrok, A Slama-Schwok, Y Cong, M Ulasli, H Schepers, M Mauthe, V 'kovski, P Kriegenburg, F Thiel, V De Haan, Cam Reggiori, F, G Crooks, G Hon, J Chandonia, S Brenner, C Franco-Munoz, D Alvarez-Diaz, Laiton- Donato, K Wiesner, M Escandon, P Usme-Ciro, J Franco-Sierra, N Florez-Sanchez, A Gomez-Rangel, S Calderon, Ldr Ramirez, J Baez, E Walteros, D Martinez, Mlo Mercado-Reyes, M, S Gerritz, C Cianci, S Kim, B Pearce, C Deminie, L Discotto, B Mcauliffe, B Minassian, S Shi, S Zhu, W Zhai, A Pendri, G Li, M Poss, S Edavettal   +99 more
openalex   +2 more sources