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Self-organization versus Watchmaker: Molecular motors and protein translocation

Biosystems, 2006
Generation of directional movement at the molecular scale is a phenomenon crucial for biological organization and dynamics. It is traditionally described in mechanistic terms, in consistency with the conventional machine-like image of the cell. The designated and highly specialized protein machines and molecular motors are presumed to bring about most ...
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Mechanical Characterization of Motor Proteins: A Molecular Dynamics Approach

Macromolecular Theory and Simulations, 2008
AbstractA new approach, based on molecular dynamics, is presented to measure the mechanical properties of motor proteins, which are important for accomplishing their intracellular functions. Two different set‐ups were designed to mimic the optical tweezers and surface force apparatus experiments. The results obtained show that the stiffness and elastic
Iuliana Aprodu   +2 more
openaire   +1 more source

Molecular shuttles based on motor proteins: active transport in synthetic environments

Reviews in Molecular Biotechnology, 2001
Active transport in cells, utilizing molecular motors like kinesin and myosin, provides the inspiration for the integration of active transport into synthetic devices. Hybrid devices, employing motor proteins in a synthetic environment, are the first prototypes of molecular shuttles.
H, Hess, V, Vogel
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Dynamic Nanodevices Based on Protein Molecular Motors

2007
Most of the present micro/nano biodevices are designed for a single use, as opposed to ‘classical’ non-biodevices (e.g., from the steam engine to the microchip). Once their function, be that simple molecular recognition like in microarrays or even biomolecular computation as in DNA computation arrays, is fulfilled and the information is passed further ...
openaire   +1 more source

Selective motor activation in organelle transport along axons

Nature Reviews Molecular Cell Biology, 2022
Sydney E Cason, Erika L F Holzbaur
exaly  

Comparative cellular analysis of motor cortex in human, marmoset and mouse

Nature, 2021
Trygve E Bakken   +2 more
exaly  

A multimodal cell census and atlas of the mammalian primary motor cortex

Nature, 2021
Edward M Callaway   +2 more
exaly  

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