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Molecular shuttles based on motor proteins: active transport in synthetic environments
Reviews in Molecular Biotechnology, 2001Active transport in cells, utilizing molecular motors like kinesin and myosin, provides the inspiration for the integration of active transport into synthetic devices. Hybrid devices, employing motor proteins in a synthetic environment, are the first prototypes of molecular shuttles.
H, Hess, V, Vogel
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Protein Linear Molecular Motor‐Powered Nanodevices
ChemInform, 2007AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
David J. G. Bakewell, Dan V. Nicolau
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Molecular circulator driven by motor proteins
Digest of Papers Microprocesses and Nanotechnology 2000. 2000 International Microprocesses and Nanotechnology Conference (IEEE Cat. No.00EX387), 2002We have fabricated a uni-directional circulator of microtubules. Since it is already technologically possible to attach foreign materials to microtubules using specific chemical or biochemical reactions, this novel technology to control the direction of microtubule movement should be applicable to drive micrometer-scaled rotating motors, or to ...
Y. Hiratsuka +4 more
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Regulation of molecular motor proteins
2001Motor proteins in the kinesin, dynein, and myosin superfamilies are tightly regulated to perform multiple functions in the cell requiring force generation. Although motor proteins within families are diverse in sequence and structure, there are general mechanisms by which they are regulated.
A R, Reilein +3 more
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Molecular Assembly of Rotary and Linear Motor Proteins
Accounts of Chemical Research, 2019Molecular machines are an important and emerging frontier in research encompassing interdisciplinary subjects of chemistry, physics, biology, and nanotechnology. Although there has been major interest in creating synthetic molecular machines, research on natural molecular machines is also crucial.
Yi Jia, Junbai Li
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Molecular movie of nucleotide binding to a motor protein
Biochimica et Biophysica Acta (BBA) - General Subjects, 2020The SecA DEAD (Asp-Glu-Ala-Asp) motor protein uses binding and hydrolysis of adenosine triphosphate (ATP) to push secretory proteins across the plasma membrane of bacteria. The reaction coordinate of nucleotide exchange is unclear at the atomic level of detail.We performed multiple atomistic computations of the DEAD motor domain of SecA with different ...
Ana-Nicoleta, Bondar +2 more
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Building artificial networks of protein molecular motors
SPIE Proceedings, 1997This study attempts to assess the feasibility of building purposefully designed molecular motor arrays, the proteins responsible for the movements of the living organisms and cells. The 'building' process used high-resolution e-beam patterning, originating in semiconductor technology, upgraded to make biomicrolithography compatible with the patterning ...
Dan V. Nicolau +5 more
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Reconstitution of Motor Proteins through Molecular Assembly
Chinese Journal of Chemistry, 2019What is the most favorite and original chemistry developed in your research group?The most favorite and original chemistry developed in my research group is about the reconstitution of motor proteins in artificially designed and assembled units. It is based on the molecular assembly technique, but the method is different from the conventional approach.
Yi Jia +5 more
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Surface Hydrophobicity Modulates the Operation of Protein Molecular Motors
2006 International Conference on Nanoscience and Nanotechnology, 2006The modulation of protein molecular motors (actin-myosin) motility has been tested on several candidate materials for microfluidics devices, all having different hydrophobicities, chemistries and nanotopographies. The analysis of the distribution of molecular properties on the molecular surface of the molecular motor protein suggests that the two very ...
Nicolau, Dan V. +4 more
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