Results 21 to 30 of about 98,232 (273)
Performance scaling and trade-offs for collective motor-driven transport
Motor-driven intracellular transport of organelles, vesicles, and other molecular cargo is a highly collective process. An individual cargo is often pulled by a team of transport motors, with numbers ranging from only a few to several hundred. We explore
Matthew P Leighton, David A Sivak
doaj +1 more source
Renewal processes and fluctuation analysis of molecular motor stepping [PDF]
We model the dynamics of a processive or rotary molecular motor using a renewal processes, in line with the work initiated by Svoboda, Mitra and Block. We apply a functional technique to compute different types of multiple-time correlation functions of ...
Alberts B +18 more
core +2 more sources
First-passage times in complex energy landscapes: a case study with nonmuscle myosin II assembly
Complex energy landscapes often arise in biological systems, e.g. for protein folding, biochemical reactions, or intracellular transport processes. Their physical effects are frequently reflected in the first-passage times (FPTs) arising from these ...
Rick Bebon, Ulrich S Schwarz
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In this work, a mathematical model was developed to relate the mechanochemical characterizations of molecular motors with the macroscopic manifestation of muscle contraction.
Jiangcheng Chen +4 more
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Dynamic mechanisms of cell rigidity sensing: insights from a computational model of actomyosin networks. [PDF]
Cells modulate themselves in response to the surrounding environment like substrate elasticity, exhibiting structural reorganization driven by the contractility of cytoskeleton. The cytoskeleton is the scaffolding structure of eukaryotic cells, playing a
Carlos Borau +4 more
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Molecular Motors–Nature’s Efficiency at Work
Nature has generated sophisticated and very efficient molecular motors, employed for nanoscale transport at the intracellular level. As a complementary tool to nanofluidics, these motors have been envisioned for nanotechnological devices.
Winfried Teizer
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From Molecules to Molecular Systems
The assembly, integration and functioning of various molecular components in complex systems is illustrated.
Ben L. Feringa
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Cooperative transport by small teams of molecular motors [PDF]
Molecular motors power directed transport of cargoes within cells. Even if a single motor is sufficient to transport a cargo, motors often cooperate in small teams.
Klumpp, Stefan +2 more
core +2 more sources
Cooperative effects enhance the transport properties of molecular spider teams [PDF]
Molecular spiders are synthetic molecular motors based on DNA nanotechnology. While natural molecular motors have evolved towards very high efficiency, it remains a major challenge to develop efficient designs for man-made molecular motors.
Frey, Erwin +2 more
core +2 more sources
Collective dynamics of molecular motors pulling on fluid membranes [PDF]
The collective dynamics of $N$ weakly coupled processive molecular motors are considered theoretically. We show, using a discrete lattice model, that the velocity-force curves strongly depend on the effective dynamic interactions between motors and ...
Campas, O. +4 more
core +5 more sources

