Results 1 to 10 of about 258,501 (145)

Aster glehni F. Schmidt Extract Modulates the Activities of HMG-CoA Reductase and Fatty Acid Synthase

Plants, 2021
Aster glehni F. Schmidt (AG), is a natural product known to have anti-obesity effects, but the mechanism underlying these effects is not well documented. We hypothesized that AG may have inhibitory effects on enzymes related to lipid accumulation. Herein,
Hyunbeom Lee, Hyoung Ja Kim, Hyungi Chae, Na Eun Yoon, Byung Hwa Jung   +4 more
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Metabolomics in Autoimmune Diseases: Focus on Rheumatoid Arthritis, Systemic Lupus Erythematous, and Multiple Sclerosis

Metabolites, 2021
The metabolomics approach represents the last downstream phenotype and is widely used in clinical studies and drug discovery. In this paper, we outline recent advances in the metabolomics research of autoimmune diseases (ADs) such as rheumatoid arthritis
Naeun Yoon, Ah-Kyung Jang, Yerim Seo, Byung Hwa Jung   +3 more
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Covalent Organic Framework/Polyacrylonitrile Electrospun Nanofiber for Dispersive Solid-Phase Extraction of Trace Quinolones in Food Samples

Nanomaterials, 2022
The extraction of quinolone antibiotics (QAs) is crucial for the environment and human health. In this work, polyacrylonitrile (PAN)/covalent organic framework TpPa–1 nanofiber was prepared by an electrospinning technique and used as an adsorbent for ...
Jinghui Zhou, An Chen, Hongying Guo, Yijun Li, Xiwen He, Langxing Chen, Yukui Zhang   +6 more
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A Highly Selective and Sensitive Fluorescent Sensor Based on Molecularly Imprinted Polymer-Functionalized Mn-Doped ZnS Quantum Dots for Detection of Roxarsone in Feeds

Nanomaterials, 2022
Roxarsone (ROX) as an organoarsenic feed additive has been widely used in livestock breeding and poultry industry, but ROX can degrade into highly toxic inorganic arsenic species in natural environments to threaten to the environment and human health ...
Fei Li, Jie Gao, Haocheng Wu, Yijun Li, Xiwen He, Langxing Chen   +5 more
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A New Ratiometric Fluorescent Probe Based on BODIPY for Highly Selective Detection of Hydrogen Sulfide

Molecules, 2022
Hydrogen sulfide (H2S) as small molecular signal messenger plays key functions in numerous biological processes. The imaging detection of intracellular hydrogen sulfide is of great significance.
Huan Xiang, Tianqing Ye, Yanbo Li, Yanfei Lin, Dan Liu, Hongwei Zhou, Jianbo Wang, Lei Li   +7 more
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Stereoselectivity control in Rh-catalyzed β-OH elimination for chiral allene formation

Nature Communications, 2023
Stereoselectivity control and understanding in the metal-catalyzed reactions are fundamental issues in catalysis. Here we report sterically controlled rhodium-catalyzed SN2’-type substitution reactions of optically active tertiary propargylic alcohols ...
Jie Wang, Wei-Feng Zheng, Xue Zhang, Hui Qian, Shengming Ma   +4 more
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DNA Nanodevice-Based Drug Delivery Systems

Biomolecules, 2021
DNA, a natural biological material, has become an ideal choice for biomedical applications, mainly owing to its good biocompatibility, ease of synthesis, modifiability, and especially programmability.
Chaoyang Guan, Xiaoli Zhu, Chang Feng
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Stainless Steel Voltammetric Sensor to Monitor Variations in Oxygen and Humidity Availability in Reinforcement Concrete Structures

Sensors, 2021
The present work presents the results obtained with a stainless steel (SS) voltammetric sensor to detect variations in humidity (H2O) and oxygen (O2) availability in concretes.
Ana Martínez-Ibernón, Josep Lliso-Ferrando, José M. Gandía-Romero, Juan Soto   +3 more
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Strategies for Enhancing the Sensitivity of Electrochemiluminescence Biosensors

Biosensors, 2022
Electrochemiluminescence (ECL) has received considerable attention as a powerful analytical technique for the sensitive and accurate detection of biological analytes owing to its high sensitivity and selectivity and wide dynamic range.
Yueyue Huang, Yuanyuan Yao, Yueliang Wang, Lifen Chen, Yanbo Zeng, Lei Li, Longhua Guo   +6 more
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Deciphering Fatty Acid Synthase Inhibition-Triggered Metabolic Flexibility in Prostate Cancer Cells through Untargeted Metabolomics

Cells, 2020
Fatty acid synthase (FAS) is a key enzyme involved in de novo lipogenesis that produces lipids that are necessary for cell growth and signal transduction, and it is known to be overexpressed, especially in cancer cells.
Ju Eun Oh, Byung Hwa Jung, Jinyoung Park, Soosung Kang, Hyunbeom Lee   +4 more
doaj   +1 more source