Results 11 to 20 of about 894,051 (294)

Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)

open access: yesProteome Science, 2017
Protein-protein interactions (PPIs) trigger a wide range of biological signaling pathways that are crucial for biomedical research and drug discovery.
Dhiraj P. Murale   +3 more
doaj   +1 more source

An antibacterial compound pyrimidomycin produced by Streptomyces sp. PSAA01 isolated from soil of Eastern Himalayan foothill

open access: yesScientific Reports, 2022
Selective isolation of soil Actinobacteria was undertaken to isolate a new class of antibiotics and bioactive molecules. A Streptomyces sp. PSAA01 (= MTCC 13,157), isolated from soil of Eastern Himalaya foothill was cultivated on a large scale for the ...
Prasenjit Das   +5 more
doaj   +1 more source

Xenon binding by a tight yet adaptive chiral soft capsule

open access: yesNature Communications, 2020
Xenon binding carries potential for xenon separation and emerging applications in magnetic resonance imaging. Here, the authors report a rare example of a tight yet soft capsule, assembled from two chiral bisurea-bisthiourea macrocycle components, that ...
Shi-Xin Nie   +5 more
doaj   +1 more source

Supramolecular tessellations by the exo-wall interactions of pagoda[4]arene

open access: yesNature Communications, 2021
Supramolecular tessellation has gained increasing interest in supramolecular chemistry for its structural aesthetics and potential applications in optics, magnetics and catalysis.
Xiao-Ni Han, Ying Han, Chuan-Feng Chen
doaj   +1 more source

Palladium-catalysed formation of vicinal all-carbon quaternary centres via propargylation

open access: yesNature Communications, 2016
Formation of vicinal, quaternary stereocentres is challenging, but such products are commonly encountered in nature. Here, the authors report a palladium catalysed process to form vicinal quaternary carbons via propargylation, including in enantiopure ...
Xin Huang   +5 more
doaj   +1 more source

Microparticles as Viral RNA Carriers from Stool for Stable and Sensitive Surveillance

open access: yesDiagnostics, 2023
Since its discovery, polymerase chain reaction (PCR) has emerged as an important technology for the diagnosis and identification of infectious diseases.
Emmanuel George Kifaro   +8 more
doaj   +1 more source

Molecular Recognition as an Information Channel: The Role of Conformational Changes [PDF]

open access: yesWorkshop on Biological and Bio-Inspired Information Theory, 43rd Annual Conference on Information Sciences and Systems, March 18-20, 2009 2009 , Page(s): 835 - 840, 2010
Molecular recognition, which is essential in processing information in biological systems, takes place in a crowded noisy biochemical environment and requires the recognition of a specific target within a background of various similar competing molecules.
arxiv   +1 more source

MolScribe: Robust Molecular Structure Recognition with Image-To-Graph Generation [PDF]

open access: yes, 2022
Molecular structure recognition is the task of translating a molecular image into its graph structure. Significant variation in drawing styles and conventions exhibited in chemical literature poses a significant challenge for automating this task. In this paper, we propose MolScribe, a novel image-to-graph generation model that explicitly predicts ...
arxiv   +1 more source

Catalytic enantioselective construction of axial chirality in 1,3-disubstituted allenes

open access: yesNature Communications, 2019
Highly enantioselective synthesis of allenes has been relying, so far, on the steric hindrance of substrates. Here the authors achieve excellent stereocontrol in the synthesis of chiral allenes with a palladium-DTBM-SEGPHOS catalytic system in a non ...
Shihua Song   +3 more
doaj   +1 more source

Differential regulation of the Epr3 receptor coordinates membrane-restricted rhizobial colonization of root nodule primordia

open access: yesNature Communications, 2017
TheLotus japonicus LysM receptor kinase EPR3 perceives rhizobial exopolysaccharides to initiate infection of the root epidermis. Here the authors show that EPR3 also mediates infection thread progression in the root cortex and show that key transcription
Yasuyuki Kawaharada   +10 more
doaj   +1 more source

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