Results 91 to 100 of about 6,976 (207)

Fact sheet for Molnupiravir. Arabic

, 2021
Title from PDF caption (viewed on January 4, 2022)."OHA4029C12292021 ARABIC"--Running footer.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

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Coronavirus M Protein Hijacks Toll‐Interacting Protein (TOLLIP) to Suppress NF‐κB Signaling and Promote Immune Evasion

MedComm, Volume 7, Issue 7, July 2026.
Under physiological conditions, pathogenic stimuli activate TLR/IL1‐R signaling, triggering TOLLIP dissociation from IRAK1 and subsequent IRAK1 phosphorylation, TRAF6 ubiquitination, and NF‐κB activation. During SARS‐CoV‐2 infection, viral M protein binds TOLLIP and stabilizes the TOLLIP–IRAK1 complex, thereby suppressing NF‐κB signaling, impairing ...
Yabin Zhang, Lu Kang, Yu Zhong, Songjun Shao, Senren Xue, Changliang Liu, Xiaoqi Zheng, Jing‐Wen Lin, Yu Chen, Fengming Luo, Huajing Wan   +10 more
wiley   +1 more source

Letter to the Editor Regarding “Impact of COVID‐19 on Hematologic Cancer Patients: Insights From the Late Pandemic Phase”

Cancer Medicine, Volume 15, Issue 10, October 2026.
Maria Mazzitelli, Pierluigi Del Vecchio, Jon Salmanton‐García, Antonella Cingolani, Livio Pagano, Carlo Torti   +5 more
wiley   +1 more source

Advancing Antiviral Design: Integrating Natural Products, Computation and Targeted Delivery

Chemical Biology &Drug Design, Volume 108, Issue 1, July 2026.
A stepwise translational framework linking natural‐product discovery, computational prioritisation, experimental validation, lead optimisation and targeted delivery is proposed to advance antiviral design. ABSTRACT The COVID‐19 pandemic highlighted the role of rapid viral mutation and global connectivity in accelerating viral emergence and spread ...
Adedayo Ayodeji Lanrewaju, Abimbola Motunrayo Folami, Saheed Sabiu, Feroz Mahomed Swalaha   +3 more
wiley   +1 more source

A Multipart Phase 1 Study to Assess Safety and Pharmacokinetics of Ibuzatrelvir in Healthy Participants and Dose Selection for a Dose‐Ranging Study

Clinical and Translational Science, Volume 19, Issue 7, July 2026.
ABSTRACT COVID‐19 continues to be a threat to global health and a burden on healthcare systems. There is an ongoing need for COVID‐19 antiviral therapies that are safe and effective across broad patient populations. Ibuzatrelvir is a potent, selective inhibitor of the SARS‐CoV‐2 main protease and demonstrated favorable properties for clinical ...
Ravi Shankar P. Singh, Sima S. Toussi, Frances Hackman, Mona Shahbazi, John Prybylski, Siddhee A. Sahasrabudhe, Penelope Crownover, Eugene P. Kadar, Billy T. George, Negar Niki Alami, Arthur Bergman   +10 more
wiley   +1 more source

Fact sheet for Molnupiravir. Spanish

, 2021
Title from PDF caption (viewed on January 4, 2022)."OHA4029C12292021 SPANISH"--Running footer.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may

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Bioluminescence imaging reveals enhanced SARS-CoV-2 clearance in mice with combinatorial regimens

iScience
Summary: Direct acting antivirals (DAAs) represent critical tools for combating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) that have escaped vaccine-elicited spike-based immunity and future coronaviruses with ...
Irfan Ullah, Fanny Escudie, Ivan Scandale, Zoela Gilani, Gabrielle Gendron-Lepage, Fleur Gaudette, Charles Mowbray, Laurent Fraisse, Renée Bazin, Andrés Finzi, Walther Mothes, Priti Kumar, Eric Chatelain, Pradeep D. Uchil   +13 more
doaj   +1 more source

Fact sheet for Molnupiravir. Chuukese

, 2021
Title from PDF caption (viewed on January 4, 2022)."OHA4029C12292021 CHUUKESE"--Running footer.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

Fact sheet for Molnupiravir. Vietnamese

, 2021
Title from PDF caption (viewed on January 4, 2022)."OHA4029C12292021 VIETNAMESE"--Running footer.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

Molnupiravir’s authorisation was premature [PDF]

BMJ, 2022
openaire   +2 more sources