Endocannabinoid control of neuroinflammation in traumatic brain injury by monoacylglycerol lipase in astrocytes. [PDF]
Neural Regen Res, 2023 Chen C.
europepmc +1 more source
A monoacylglycerol lipase inhibitor showing therapeutic efficacy in mice without central side effects or dependence. [PDF]
Nat Commun, 2023 Jiang M +28 more
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A Highly Specific Monoacylglycerol Lipase PROTAC Probe
The key role of monoacylglycerol lipase (MAGL) in signaling pathways involving endocannabinoids and eicosanoids makes it a promising therapeutic target for numerous diseases, such as (neuro)inflammatory and neuropsychiatric disorders, along with acute tissue damage and cancer.
Axel Hentsch +22 more
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Endocannabinoid enzymes monoacylglycerol lipase and diacylglycerol lipase [PDF]
, 2021 openaire +1 more source
Sexually dimorphic effects of monoacylglycerol lipase inhibitor MJN110 on stress-related behaviour and drinking in Marchigian Sardinian alcohol-preferring rats. [PDF]
Br J Pharmacol, 2023 Vozella V +9 more
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Monoacylglycerol lipase regulates macrophage polarization and cancer progression in uveal melanoma and pan-cancer. [PDF]
Front Immunol, 2023 Tan Y +7 more
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Monoacylglycerol Lipase Protects the Presynaptic Cannabinoid 1 Receptor from Desensitization by Endocannabinoids after Persistent Inflammation. [PDF]
J Neurosci, 2023 Bouchet CA +4 more
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