Results 121 to 130 of about 11,083 (203)

The possible link between endocannabinoid system gene polymorphisms and overweight/obesity susceptibility in individuals living in the Marmara Region

Türk Biyokimya Dergisi
Obesity is a global health problem related to reduced life quality and shorter life expectancy. Given the fact that genetic factors play a role in obesity development, studies have suggested that polymorphisms of cannabinoid receptor 1 (CNR1 ...
Altun Beril, Cok İsmet, Noyan Cemal Onur, Kadioglu Ela, Cetin Alptekin, Sengezer Tijen, Altintas Merih, Kurnaz Samet, Dilbaz Nesrin   +8 more
doaj   +1 more source

Produção de diacilgliceróis a partir da glicerólise enzimática de óleo de peixe utilizando meio com surfactante de grau alimentício [PDF]

, 2011
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia de Alimentos, Florianópolis, 2011Nas pesquisas com óleos e gorduras alimentícios, estudos vêm indicando que os produtos ricos em ...
Santos, Joanna Silva
core  

A patent review of Monoacylglycerol Lipase (MAGL) inhibitors (2013-2017)

, 2017
Introduction: Monoacylglycerol lipase is a serine hydrolase that plays a major role in the degradation of the endocannabinoid 2-arachidonoylglycerol. Because of this key role, selective inactivation of MAGL represents an interesting approach to obtain ...
Filippo Minutolo, Granchi, Carlotta, Isabella Caligiuri, Tuccinardi, Tiziano, Rizzolio, Flavio, Caligiuri, Isabella, Tiziano Tuccinardi, Minutolo, Filippo, Carlotta Granchi, Flavio Rizzolio   +9 more
core   +1 more source

The effects of fatty acid amide hydrolase and monoacylglycerol lipase inhibitor treatments on lipopolysaccharide-induced airway inflammation in mice

, 2020
Cannabinoids and the endocannabinoid system significantly contributes to the airway inflammation. Fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) are two main enzymes responsible for the metabolism of the endocannabinoids anandamide (
Nemutlu, EMİRHAN, Onder, SC, Sahin-Erdemli, I, Abohalaka, R, Bozkurt, TURGUT EMRAH   +4 more
core   +1 more source

Design, Synthesis, and Evaluation of ¹⁸F‑Labeled Monoacylglycerol Lipase Inhibitors as Novel Positron Emission Tomography Probes

, 2019
Dysfunction of monoacylglycerol lipase (MAGL) is associated with several psychopathological disorders, including drug addiction and neurodegenerative diseases.
Zhen Chen (129176), Michael A. Schafroth (1771792), Steven H. Liang (1341546), Akiko Hatori (136785), Jun-An Ma (1393726), Wakana Mori (1428892), Xiaofei Zhang (136103), Lu Wang (45927), Hualong Fu (1414090), Kuan Hu (3349553), Yiding Zhang (1428880), Lee Josephson (289121), Thomas L. Collier (3637486), Xiaoyun Deng (6407987), Daisuke Ogasawara (1452202), Qingzhen Yu (6407984), Tuo Shao (6407981), Richard S. Van (7435541), Pilar Giffenig (6407990), Ming-Rong Zhang (136828), Masayuki Fujinaga (136798), Yihan Shao (1338777), Jian Rong (598108), Genwei Zhang (4028228), Vasily Belov (334968), Mikhail I. Papisov (7435544), Benjamin F. Cravatt (93774)   +26 more
core   +2 more sources

Monoacylglycerol lipase (MAGL) [PDF]

Science-Business eXchange, 2011
openaire   +2 more sources

Discovery of reversible monoacylglycerol lipase inhibitors

, 2022
Monoacylglycerol lipase (MAGL) is the principal enzyme responsible for hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-AG). MAGL inhibition provides several potential therapeutic opportunities, including anti-nociceptive, anti-inflammatory ...
Jiang, M.
core  

Therapeutic Potential of Fatty Acid Amide Hydrolase, Monoacylglycerol Lipase, and N -Acylethanolamine Acid Amidase Inhibitors

, 2016
International audienceFatty acid ethanolamides (FAEs) and endocannabinoids (ECs) have been shown to alleviate pain and inflammation, regulate motility and appetite, and produce anticancer, anxiolytic, and neuroprotective efficacies via cannabinoid ...
Sansook, Supojjanee, Regis Millet (16239371), Chavatte, Philippe, Spencer, John, Tuo, Wei, Natascha Leleu-Chavain (3130482), Supojjanee Sansook (3130485), Millet, Régis, John Spencer (4461472), Leleu-Chavain, Natascha, Wei Tuo (3130491), Philippe Chavatte (655568)   +11 more
core   +1 more source

Synthesis of monoacylglycerol containing pinolenic acid via stepwise esterification using a cold active lipase

, 2017
High purity monoacylglycerol (MAG) containing pinolenic acid was synthesized via stepwise esterification of glycerol and fatty acids from pine nut oil using a cold active lipase from Penicillium camembertii as a biocatalyst. Effects of temperature, molar
김양하
core   +1 more source

Endocannabinoid control of neuroinflammation in traumatic brain injury by monoacylglycerol lipase in astrocytes. [PDF]

Neural Regen Res, 2023
Chen C.
europepmc   +1 more source