Results 141 to 150 of about 68,881 (203)

Discovering monoacylglycerol lipase inhibitors by a combination of fluorogenic substrate assay and activity-based protein profiling. [PDF]

Front Pharmacol, 2022
Deng H, Zhang Q, Lei Q, Yang N, Yang K, Jiang J, Yu Z.   +6 more
europepmc   +1 more source

Highly Specific Miniaturized Fluorescent Monoacylglycerol Lipase Probes Enable Translational Research. [PDF]

J Am Chem Soc
Hentsch A, Guberman M, Radetzki S, Kaushik S, Huizenga M, He Y, Contzen J, Kuhn B, Benz J, Schippers M, Paul J, Leibrock L, Collin L, Wittwer M, Topp A, O'Hara F, Heer D, Hochstrasser R, Blaising J, von Kries JP, Mu L, van der Stelt M, Mergenthaler P, Lipstein N, Grether U, Nazaré M.   +25 more
europepmc   +1 more source

Enhancement of the endocannabinoid system through monoacylglycerol lipase inhibition relieves migraine-associated pain in mice. [PDF]

J Headache Pain
Mangutov E, Awad-Igbaria Y, Siegersma K, Gastambide F, Asuni AA, Pradhan AAA.   +5 more
europepmc   +1 more source

Development of a novel ¹⁸F-labeled reversible-binding radioligand for imaging monoacylglycerol lipase with positron emission tomography. [PDF]

Acta Pharm Sin B
Rong J, Zhao C, Chaudhary AF, Ware T, Van RS, Li Y, Calderon Leon ER, Dang V, Chen J, Xiao Z, Zhou X, Zhang W, Bi C, Zhang K, Patel JS, Shao Y, Ran C, Collin L, Haider A, Cravatt BF, Liang SH.   +20 more
europepmc   +1 more source

Targeting Monoacylglycerol Lipase in Pursuit of Therapies for Neurological and Neurodegenerative Diseases. [PDF]

Molecules, 2021
Zanfirescu A, Ungurianu A, Mihai DP, Radulescu D, Nitulescu GM.   +4 more
europepmc   +1 more source

Genome-wide characterization of monoacylglycerol lipase (MAGL) gene family in soybean and functional analysis of GmMAGLs in storage lipid metabolism and drought resistance. [PDF]

BMC Genomics
Jing H, Sun Y, Wang B, Ma J, Wan K, Li Z, Zhou Y, Li R, Zhang H, Xue J.   +9 more
europepmc   +1 more source

Inhibition of Monoacylglycerol Lipase by NSD1819 as an Effective Strategy for the Endocannabinoid System Modulation against Neuroinflammation-Related Disorders. [PDF]

Int J Mol Sci, 2022
Micheli L, Maramai S, Toti A, Ferrara V, Ciampi C, Di Cesare Mannelli L, Ghelardini C.   +6 more
europepmc   +1 more source

Novel Heterocyclic Compounds as Monoacylglycerol Lipase Inhibitors for Treating Multiple Diseases. [PDF]

ACS Med Chem Lett
Sabnis RW.
europepmc   +1 more source

Structure-Activity Relationship Studies of Aryl Sulfoxides as Reversible Monoacylglycerol Lipase Inhibitors. [PDF]

J Med Chem
Jiang M, Huizenga MCW, Mohr F, Amedi A, Bakker R, van den Berg RJBHN, Deng H, van der Wel T, van Boeckel CAA, van der Stelt M.   +9 more
europepmc   +1 more source

Novel Pyrazolopyridine Inhibitors of Monoacylglycerol Lipase for the Treatment of Neurodegenerative Diseases and Neuroinflammation. [PDF]

ACS Med Chem Lett
Rosse G.
europepmc   +1 more source