Results 81 to 90 of about 9,642 (173)

Localization of diacylglycerol lipase alpha and monoacylglycerol lipase during postnatal development of the rat retina

Frontiers in Neuroanatomy, 2014
In recent decades, there has been increased interest in the physiological roles of the endocannabinoid (eCB) system and its receptors, the cannabinoid receptor types 1 (CB1R) and 2 (CB2R).
Bruno eCécyre, Bruno eCécyre, Marjorie eMonette, Liza eBeudjekian, Christian eCasanova, Jean-Francois eBouchard   +5 more
doaj   +1 more source

A novel method for measuring human hepatic lipase activity in postheparin plasma

Journal of Lipid Research, 2007
The objective of this study was to establish a hepatic lipase (HL) assay method that can be applied to automatic clinical analyzers. Seventy-four hyperlipidemic subjects (men/women 45/29) were recruited. Lipase activity was assayed measuring the increase
S. Imamura, J. Kobayashi, S. Sakasegawa, A. Nohara, K. Nakajima, M. Kawashiri, A. Inazu, M. Yamagishi, J. Koizumi, H. Mabuchi   +9 more
doaj   +1 more source

A first attempt into the production of acylglycerol mixtures from Echium oil

Frontiers in Bioengineering and Biotechnology, 2016
Enzymatic glycerolysis of Echium oil (Echium plantagineum) has been carried out in the presence of four commercial lipases. Different pretreatment of the reaction mixture, such as high pressure homogenization and addition of food grade monoolein as an ...
Luis eVázquez, Alejandro eJordán, Guillermo eReglero, Guillermo eReglero, Carlos F Torres   +4 more
doaj   +1 more source

Monoacylglycerol lipase promotes progression of hepatocellular carcinoma via NF-κB-mediated epithelial-mesenchymal transition

Journal of Hematology & Oncology, 2016
Background Monoacylglycerol lipase (MAGL), a critical lipolytic enzyme, has emerged as a key regulator of tumor progression, yet its biological function and clinical significance in hepatocellular carcinoma (HCC) is still unknown.
Weiping Zhu, Yiming Zhao, Jiamin Zhou, Xin Wang, Qi Pan, Ning Zhang, Longrong Wang, Miao Wang, Dihua Zhan, Zeyang Liu, Xigan He, Dening Ma, Shuang Liu, Lu Wang   +13 more
doaj   +1 more source

Lipases are differentially regulated by hormones to maintain free fatty acid homeostasis for insect brain development

BMC Biology
Background Free fatty acids (FFAs) play vital roles as energy sources and substrates in organisms; however, the molecular mechanism regulating the homeostasis of FFA levels in various circumstances, such as feeding and nonfeeding stages, is not fully ...
Yan-Xue Li, Qiao Yan, Tian-Wen Liu, Jin-Xing Wang, Xiao-Fan Zhao   +4 more
doaj   +1 more source

Intestinal monoacylglycerol metabolism: developmental and nutritional regulation of monoacylglycerol lipase and monoacylglycerol acyltransferase.

The Journal of biological chemistry, 2008
Intestinal monoacylglycerol (MG) metabolism is well known to involve its anabolic reesterification to triacylglycerol (TG). We recently provided evidence for enterocyte MG hydrolysis and demonstrated expression of the monoacylglycerol lipase (MGL) gene in human intestinal Caco-2 cells and rodent small intestinal mucosa.
Su-Hyoun, Chon, Yin Xiu, Zhou, Joseph L, Dixon, Judith, Storch   +3 more
openaire   +1 more source

The possible link between endocannabinoid system gene polymorphisms and overweight/obesity susceptibility in individuals living in the Marmara Region

Türk Biyokimya Dergisi
Obesity is a global health problem related to reduced life quality and shorter life expectancy. Given the fact that genetic factors play a role in obesity development, studies have suggested that polymorphisms of cannabinoid receptor 1 (CNR1 ...
Altun Beril, Cok İsmet, Noyan Cemal Onur, Kadioglu Ela, Cetin Alptekin, Sengezer Tijen, Altintas Merih, Kurnaz Samet, Dilbaz Nesrin   +8 more
doaj   +1 more source

Monoacylglycerol lipase (MAGL) [PDF]

Science-Business eXchange, 2011
openaire   +2 more sources

Linoleic acid in diets of mice increases total endocannabinoid levels in bowel and liver: modification by dietary glucose

Obesity Science & Practice, 2019
Summary Aim Linoleic acid (LA) is an essential fatty acid involved in the biosynthesis of arachidonic acid and prostaglandins. LA is known to induce obesity and insulin resistance. In this study, two concentrations of LA with or without added glucose (G)
S. Ghosh, J. F. O'Connell, O. D. Carlson, I. González‐Mariscal, Y. Kim, R. Moaddel, P. Ghosh, J. M. Egan   +7 more
doaj   +1 more source

Cetirizine and Levetiracetam as Inhibitors of Monoacylglycerol Lipase: Investigating Their Repurposing Potential as Novel Osteoarthritic Pain Therapies. [PDF]

Pharmaceuticals (Basel), 2023
Andrei C, Mihai DP, Nitulescu G, Ungurianu A, Margina DM, Nitulescu GM, Olaru OT, Busca RM, Zanfirescu A.   +8 more
europepmc   +1 more source