Amphetamine Derivatives as Monoamine Oxidase Inhibitors [PDF]
Frontiers in Pharmacology, 2020 Amphetamine and its derivatives exhibit a wide range of pharmacological activities, including psychostimulant, hallucinogenic, entactogenic, anorectic, or antidepressant effects.
Miguel Reyes-Parada +3 more
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Effects of Natural Monoamine Oxidase Inhibitors on Anxiety-Like Behavior in Zebrafish [PDF]
Frontiers in Pharmacology, 2021 Monoamine oxidases (MAO) are a valuable class of mitochondrial enzymes with a critical role in neuromodulation. In this study, we investigated the effect of natural MAO inhibitors on novel environment-induced anxiety by using the zebrafish novel tank ...
Oihane Jaka +8 more
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Quercetin and Related Chromenone Derivatives as Monoamine Oxidase Inhibitors: Targeting Neurological and Mental Disorders [PDF]
Molecules, 2019 Monoamine oxidase inhibitions are considered as important targets for the treatment of depression, anxiety, and neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases.
Priyanka Dhiman +4 more
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Natural based piperine derivatives as potent monoamine oxidase inhibitors: an in silico ADMET analysis and molecular docking studies [PDF]
BMC Chemistry, 2020 Neurodegenerative disorders follow numerous pathological ways concerning overexpression of monoamine oxidase and formation of reactive oxygen species.
Priyanka Dhiman +2 more
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Monoamine Oxidase Inhibitors in Drug Discovery Against Parkinson’s Disease: An Update [PDF]
PharmaceuticalsBackground: Parkinson’s disease (PD) is a progressive neurodegenerative disorder with substantial socioeconomic impact, characterized by the gradual loss of dopaminergic neurons, dopamine deficiency, and pathological processes such as neuroinflammation ...
Luana Vergueiro Ribeiro +3 more
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2-acetylphenol analogs as potent reversible monoamine oxidase inhibitors [PDF]
Drug Design, Development and Therapy, 2015 Lesetja J Legoabe,1 Anél Petzer,1 Jacobus P Petzer1,21Centre of Excellence for Pharmaceutical Sciences, 2Department of Pharmaceutical Chemistry, School of Pharmacy, North-West University, Potchefstroom, South AfricaAbstract: Based on a previous ...
Legoabe LJ, Petzer A, Petzer JP
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Piperidine: A Versatile Heterocyclic Ring for Developing Monoamine Oxidase Inhibitors [PDF]
ACS Omega, 2023 Jayalakshmi Jayan +11 more
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Monoamine oxidase inhibitors [PDF]
Anaesthesia, 1964 Publisher Summary This chapter describes the various classes of chemical compounds, which have an inhibitory action on monoamine oxidase (MAO). The chapter discusses the current theories of the function of monoamine oxidase and the possible mechanism by which the MAO inhibitors (MAOI) react with MAO.
Gerald Garmany, R.R.P. Warner
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Molecules, 2021 Despite not being utilized as considerably as other antidepressants in the therapy of depression, the monoamine oxidase inhibitors (MAOIs) proceed to hold a place in neurodegeneration and to have a somewhat broad spectrum in respect of the treatment of ...
Tapan Behl +9 more
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Molecular docking approach of monoamine oxidase B inhibitors for identifying new potential drugs: Insights into drug-protein interaction discovery [PDF]
Journal of Cell and Molecular Research, 2013 Monoamine oxidase (EC, 1.4.3.4) or amine oxidoreductase catalyzes the oxidative deamination of biogenic amines. Abnormal action of the monoamine oxidase B has been associated with neurological dysfunctions including parkinson´s disorder.
Salimeh Raeisi
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