Results 151 to 160 of about 13,009 (197)
Basigin mediation of Plasmodium falciparum red blood cell invasion does not require its transmembrane domain or interaction with monocarboxylate transporter 1. [PDF]
PLoS PathogKing NR +5 more
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Intestinal monocarboxylate transporter 1 mediates lactate transport in the gut and regulates metabolic homeostasis of mouse in a sex-dimorphic pattern. [PDF]
Life MetabWang S +8 more
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Monocarboxylate Transport Matters
New England Journal of Medicine, 2014The liver makes ketone bodies (3-hydroxybutyrate, acetoacetate, and acetone, the breakdown product of acetoacetate) from fat when intracellular glucose is in short supply — for example, in starvation or unregulated diabetes. The generated 3-hydroxybutyrate and acetoacetate serve as alternative energy sources for the cells.
Linda H, Bergersen, Tore, Eid
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Thyroid hormone transport by monocarboxylate transporters
Best Practice & Research Clinical Endocrinology & Metabolism, 2007Thyroid hormone (TH) is essential for the normal development and metabolism of different tissues. TH action and metabolism take place intracellularly, which requires cellular uptake via transporters. Several transporter families have been identified, of which the monocarboxylate transporter (MCT) family deserves special attention.
Visser, W. Edward +3 more
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Role of monocarboxylate transporters and glucose transporters in prostate cancer
Urologia Journal, 2022Objectives: Currently, research of new diagnostic approaches to detect clinically significant prostate cancer is relevant because of the importance of early detection of aggressive forms of the disease, often challenging, even when using modern diagnostic tools.
Stanislav Vovdenko +4 more
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Monocarboxylate transport in erythrocytes
The Journal of Membrane Biology, 1982Transport of anions across the red blood cell membrane has been studied intensively in recent years under the impact of the successful identification and molecular characterization of the transport protein mediating chloride/bicarbonate exchange. The features of this electrically silent exchange process which is mediated by a 95-K Dalton intrinsic ...
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Comprehensive Physiology, 2013
Abstract Monocarboxylates such as lactate, pyruvate, and the ketone bodies play major roles in metabolism and must be transported across both the plasma membrane and mitochondrial inner membrane. A family of five proton‐linked MonoCarboxylate Transporters (MCTs) is involved in the former and the mitochondrial ...
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Abstract Monocarboxylates such as lactate, pyruvate, and the ketone bodies play major roles in metabolism and must be transported across both the plasma membrane and mitochondrial inner membrane. A family of five proton‐linked MonoCarboxylate Transporters (MCTs) is involved in the former and the mitochondrial ...
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Monocarboxylate transporters in subsarcolemmal and intermyofibrillar mitochondria
Biochemical and Biophysical Research Communications, 2004Whether subsarcolemmal (SS) and intermyofibrillar (IMF) mitochondria contain monocarboxylate transporters (MCTs) is controversial. We have examined the presence of MCT1, 2, and 4 in highly purified SS and IMF mitochondria. These mitochondria were not contaminated with plasma membrane, sarcoplasmic reticulum or endosomal compartments, as the marker ...
Carley R, Benton +4 more
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