Results 221 to 230 of about 737,831 (351)

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

Advanced Science, EarlyView.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang, Xi Dai, Shuaihu Li, Yingxue Chen, Yaxin Yu, Lin Wang, Kun Liu, Shuhan Lyu, Chongyang Li, Yihua Sun, Fei Li   +10 more
wiley   +1 more source

Monocytes acquire a tumor-associated IL1B program upon encountering patient-derived colon cancer organoids. [PDF]

Oncoimmunology
Balzasch BM, von Kries A, Hüll S, Shaltiel IA, Boonekamp KE, Ast V, Burgermeister E, Betge J, Ebert M, Boutros M, Helming L, Umansky V, Cerwenka A.   +12 more
europepmc   +1 more source

The role of monocyte subsets in HIV-1 pathogenesis and their contribution to the viral reservoir.

, 2017
Emma Tippett
openalex   +1 more source

Author response: Single cell analysis reveals human cytomegalovirus drives latently infected cells towards an anergic-like monocyte state

, 2020
Miri Shnayder, Aharon Nachshon, Batsheva Rozman, Biana Bernshtein, Michael Lavi, Noam Fein, Emma Poole, Selmir Avdic, Emily Blyth, David Gottlieb, Allison Abendroth, Barry Slobedman, John Sinclair, Noam Stern‐Ginossar, Michal Schwartz   +14 more
openalex   +1 more source

The IL-12 Response of Primary Human Dendritic Cells and Monocytes to Toxoplasma gondii Is Stimulated by Phagocytosis of Live Parasites Rather Than Host Cell Invasion [PDF]

, 2015
Kevin Tosh, Lara Mittereder, Sandra Bonne-Année, Sara Hieny, Thomas B. Nutman, Steven M. Singer, Alan Sher, Dragana Janković   +7 more
openalex   +1 more source

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Itch‐induced tick removal (IITR): An acquired neuroimmune mechanism, itch‐induced tick removal, develops after repeated tick exposure, mobilizing T cells and macrophages at the tick bite site to trigger a rapid scratching response that facilitates timely tick removal within a critical window that precedes the transmission of many tick‐borne pathogens ...
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

Synovial fluid potentiates local fibroblasts to drive monocyte activation in juvenile idiopathic arthritis. [PDF]

Arthritis Res Ther
Schmidt T, Mossberg A, Król P, Kapetanovic MC, Einarsson JT, Croft AP, Bengtsson AA, Kahn F, Kahn R.   +8 more
europepmc   +1 more source

Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration

Advanced Science, EarlyView.
Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman, Carla Alvarez Rivas, Aashish Srivastava, Nora Marek, Kamal Mustafa, Alpdogan Kantarci   +5 more
wiley   +1 more source

Percentage of CD56⁺ monocytes at neutrophil engraftment is associated with the incidence of acute graft-versus-host disease. [PDF]

Ann Hematol
Hashimoto K, Sato T, Ishikawa Y, Okuhiro Y, Sugiyama D, Zhang H, Ito S, Inagaki Y, Miyao K, Sawa M, Morishita T, Goto T, Nishida T, Fukushima N, Ozeki K, Hanajiri R, Terakura S, Nishikawa H, Kiyoi H.   +18 more
europepmc   +1 more source

Defective monocyte-to-macrophage maturation in patients with aplastic anemia [PDF]

, 1989
Reinhard Andreesen, Wolfram Brugger, C. Thomssen, Annegret Rehm, B Speck, G. W. Löhr   +5 more
openalex   +1 more source