Results 211 to 220 of about 84,373 (257)

Opportunities and Challenges of mRNA and VLP Technologies for Pan-Flavivirus Vaccine Development: Focus on Conserved Quaternary Epitope Conformations. [PDF]

Int J Mol Sci
Pinzon Burgos EF, Camacho Ortega S, Atkinson B, Chua JV, Heredia A.   +4 more
europepmc   +1 more source

Polymeric α‐Hairpinin Allergens Induce a Functional Response via a Single Antibody

Allergy, EarlyView.
Gage O. Leighton, Taylor M. Cosey, Emmanuel R. De Diavoukana, Isabelle R. Lytle, Alexander C. Y. Foo, Lars C. Pedersen, Scott A. Gabel, Robert M. Petrovich, Min Shi, Venu Aruva, Paige Creeks, Joyce J. W. Wong, Jian Zhang, R. Stokes Peebles Jr., Derek Croote, Scott A. Smith, Geoffrey A. Mueller   +16 more
wiley   +1 more source

Characterisation of a cold‐adapted, thermostable glucokinase from psychrophilic Pseudoalteromonas sp. AS‐131 reveals how the enzyme achieves high thermal stability without loss of cold adaptation

The FEBS Journal, EarlyView.
We investigated glucokinase from the psychrophilic Pseudoalteromonas sp. AS‐131 (PsGK), which was isolated from the Antarctic Ocean. Biochemical studies revealed that PsGK is a cold‐adapted enzyme with high thermal stability, in contrast to general cold‐adapted enzymes, which have low thermal stability.
Akane Yato, Yuki Kato, Fuyuko Hayashi, Rio Asaka, Atsuko Ogawa, Tokuro Oda, Sayaka Tsuji, Masashi Unno, Nobuaki Soh, Keiichi Watanabe, Masaki Horitani   +10 more
wiley   +1 more source

Crystal Structure of Měnglà Virus Nucleoprotein Bound by a Poorly Cross-Reactive Anti-Marburg Virus Nanobody Highlights a Single Amino Acid Affinity Switch, a Feature Also Evident in Dehong Virus. [PDF]

ACS Infect Dis
Sherwood LJ, Taylor AB, Olsen SK, Hayhurst A.   +3 more
europepmc   +1 more source

Anemia‐associated mutations disrupt the CDIN1‐Codanin1 complex in inherited congenital dyserythropoietic anemia I (CDA‐I) disease

The FEBS Journal, EarlyView.
Congenital dyserythropoietic anemia type I (CDA‐I) arises from mutations in Codanin1 and CDIN1. Using quantitative biophysical approaches, we show that disease‐associated mutations disrupt the CDIN1‐Codanin1 complex. Our findings provide critical insights into the molecular mechanism that links protein dysfunction to disturbing chromatin arrangement ...
Martin Stojaspal, Tomas Brom, Ivona Nečasová, Tomáš Janovič, Pavel Veverka, Naina Verma, Lukáš Uhrík, Lenka Hernychova, Ctirad Hofr   +8 more
wiley   +1 more source

Parkinson's disease-specific α-Synuclein variants potentially drive Lewy body formation by engaging in promiscuous and non-functional interactions. [PDF]

Commun Biol
Jos S, Shivanandaswamy N, Sharma A, Prasad TK, Kashyap R, Kamariah N, Bharath MMS, Sharma D, Nath S, Padmanabhan B, Padavattan S.   +10 more
europepmc   +1 more source

The potential cytotoxic effect of recent universal adhesives with modified monomeric compositions on human gingival epithelial cells. [PDF]

Sci Rep
El-Maksoud OA, Sultan N, Ismail HS, Wafaie RA, Hamama HH, Mahmoud SH.   +5 more
europepmc   +1 more source

Computational Pipeline for Accelerating the Design of Glycomimetics. [PDF]

J Chem Inf Model
Xiao Y, Lee AH, Mahmoud S, Sameem B, Wentworth D, Wang X, Miller GD, Grant OC, Foley BL, Woods RJ.   +9 more
europepmc   +1 more source

Editorial: Community series in biology of C-reactive protein, volume II. [PDF]

Front Immunol
Agrawal A, Wu Y.
europepmc   +1 more source

C-reactive protein dissociation drives choroidal neovascularization in age-related macular degeneration. [PDF]

Sci Rep
Hernandez M, Romero-Vázquez S, Recalde S, Bezunartea J, Orduña MM, Belza-Zuazu I, García-Layana A, Adán A, Fernández-Robredo P, Molins B.   +9 more
europepmc   +1 more source