Results 91 to 100 of about 7,647 (170)

Tea and Blood–Brain Barrier Homeostasis: Potential Mechanisms and Improvement Strategies

open access: yesFood Frontiers, Volume 6, Issue 6, Page 2673-2697, November 2025.
Abstract The blood–brain barrier (BBB), a selective interface regulating cerebral substance exchange, plays a crucial role in maintaining cognitive function and metabolic balance. While tea consumption has been traditionally associated with health benefits, its specific effects on BBB integrity warrant systematic investigation. This review demonstrates
Rongbosen Yue   +5 more
wiley   +1 more source

Role of Ischemic Preconditioning in the Cardioprotective Mechanisms of Monomeric C-Reactive Protein-Deposited Myocardium in a Rat Model

open access: yesJournal of Chest Surgery, 2021
Background: The deposition of monomeric C-reactive protein (mCRP) in the myocardium aggravates ischemia-reperfusion injury (IRI) and myocardial infarction. Ischemic preconditioning (IPC) is known to protect the myocardium against IRI.
Eun Na Kim   +4 more
doaj   +1 more source

Efficient Synthesis of Narrowly Dispersed Brush Polymers via Living Ring-Opening Metathesis Polymerization of Macromonomers [PDF]

open access: yes, 2009
Various macromonomers (MMs) were efficiently synthesized through the copper-catalyzed “click” coupling of a norbornene moiety to the chain end of poly(methylacrylate), poly(t-butylacrylate), and polystyrene that were prepared using atom transfer radical ...
Grubbs, Robert H.   +2 more
core   +1 more source

Use of monomeric and oligomeric flavanols in the dietary management of patients with type 2 diabetes mellitus and microalb [PDF]

open access: yes, 2018
__Background:__ Patients with type 2 diabetes mellitus (T2D) are prone to micro- and macro-vascular complications. Monomeric and oligomeric flavanols (MOF) isolated from grape seeds (Vitis vinifera) have been linked to improved endothelial function and ...
Athumani, A.A. (Athumani A.)   +9 more
core   +2 more sources

Beyond Aggregation: Engineering AIEgens from Molecular Design to Supramolecular Assembly for Advanced Photophysical Function

open access: yesSmall Structures, Volume 6, Issue 11, November 2025.
This review presents a concise overview of aggregation‐induced emission luminogens, emphasizing molecular design and supramolecular assembly strategies to modulate their photophysical properties in the aggregated state. By summarizing and highlighting recent advances, it offers valuable insights to guide the development and design of high‐performance ...
Yingtong Luo   +3 more
wiley   +1 more source

Regulation, sensory domains and roles of two Desulfovibrio desulfuricans ATCC27774 Crp family transcription factors, HcpR1 and HcpR2, in response to nitrosative stress [PDF]

open access: yes, 2016
In silico analyses identified a Crp/Fnr family transcription factor (HcpR) in sulfate-reducing bacteria that controls expression of the hcp gene, which encodes the hybrid cluster protein and contributes to nitrosative stress responses.
Browning, D.   +9 more
core   +2 more sources

Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects

open access: yesImmunology, Volume 176, Issue 3, Page 277-303, November 2025.
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder   +4 more
wiley   +1 more source

Dissociation of C-Reactive Protein Localizes and Amplifies Inflammation: Evidence for a Direct Biological Role of C-Reactive Protein and Its Conformational Changes

open access: yesFrontiers in Immunology, 2018
C-reactive protein (CRP) is a member of the pentraxin superfamily that is widely recognized as a marker of inflammatory reactions and cardiovascular risk in humans.
James D. McFadyen   +10 more
doaj   +1 more source

Synthesis and Characterization of Py(PCL), Py(PLLA) Homopolymers and Py(PCL‐b‐PLLA) Copolymer via Ring‐Opening Polymerization: Determination of Structural, Optical, and Biocompatible Properties

open access: yesAdvanced Materials Interfaces, Volume 12, Issue 19, October 6, 2025.
This work investigates by the ROP process the chemical structure, thermal, optical and biocompatibility with living cells of the pyrene‐functionalized Py(PCL), Py(PLLA) homopolymers, and Py(PCL‐b‐PLLA) copolymers. It thoroughly confirms their stability, great fluorescence, and capacity to support MCF‐7 cell growth.
Murat Mısır   +6 more
wiley   +1 more source

High prevalence of autoantibodies against monomeric C reactive protein (CRP) in children with PFAPA syndrome [PDF]

open access: yesJournal of Medical Biochemistry, 2018
PFAPA (periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis) syndrome is an autoinflammatory disorder of unknown etiology. The aim of our study was to evaluate whether the presence of anti-mCRP autoantibodies (anti-mCRP) might possibly ...
Kraszewska-Glomba Barbara   +3 more
doaj  

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