Results 41 to 50 of about 88,343 (296)
Advanced Science, EarlyView.Boronic acid‐based fluorescent hybrids have been used as part of a versatile platform for real‐time metabolic bioimaging across cellular and organismal scales. Including glucose‐responsive imaging in living cells and in an insulin‐deficient vertebrate model, this work opens new opportunities for the development of precision diagnostics, metabolic ...
Haobo Ge +13 more
wiley +1 more source
Elevated Serum Mannose Levels as a Marker of Polycystic Ovary Syndrome
Frontiers in Endocrinology, 2019 Background: Recent reports have highlighted the role of monosaccharide biosynthesis in the pathogenesis of polycystic ovary syndrome (PCOS), suggesting that these processes may serve as a biomarker in PCOS.
Di Feng +7 more
doaj +1 more source
Elevated Serum Leptin Levels as a Predictive Marker for Polycystic Ovary Syndrome
Frontiers in Endocrinology, 2022 BackgroundLeptin may have important implications in polycystic ovary syndrome (PCOS)-related metabolic disorders. However, the changes in serum leptin levels in patients with PCOS and its predictive value for PCOS remain obscure. We intend to analyze the
Yuanyuan Peng +9 more
doaj +1 more source
Advanced Science, EarlyView.Oligosaccharides with defined glycosidic bonds drive divergent gut microbial succession and shape unique metabolic profiles. Absolute time‐series profiling with Bayesian generalized Lotka–Volterra modeling identifies bond‐specific microbial responders, while monoculture validation and metaproteomics reveal linkage‐matched transport and cleavage modules.
Xiaoxuan Lu +10 more
wiley +1 more source
A Malonyl-Based Scaffold for Conjugatable Multivalent Carbohydrate-BODIPY Presentations
Molecules, 2019 A concise synthetic route from methylmalonate to a tetravalent aliphatic scaffold has been developed. The ensuing tetra-tethered derivative is equipped with two hydroxyl groups, as well as orthogonal alkene and alkyne functionalities.
Clara Uriel +4 more
doaj +1 more source
Monosaccharide composition of cell walls from various organs.
, 2016 Monosaccharide composition of cell walls from various organs.
Jian-Min Wan (381111) +16 more
core +1 more source
Advanced Science, EarlyView.TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu +12 more
wiley +1 more source
Proximity‐Induced Protein Deglycosylation by Endogenous O‐GlcNAcase
Angewandte Chemie, EarlyView.Bifunctional molecules recruit endogenous O‑GlcNAcase to target proteins, enabling selective de‑O‑GlcNAcylation in living cells without perturbing global O‑GlcNAc homeostasis. This work developed a programmable chemical strategy for targeted O‑GlcNAc editing and framework for functional enzymatic recruitment via optimization of competitive enzyme ...
Haixing Xu +4 more
wiley +2 more sources
CyTA - Journal of Food, 2017 A simple, sensitive, and specific capillary electrophoretic method based on 1-phenyl-3-methyl-5-pyrazolon (PMP) derivatization has been developed for simultaneous separation and determination of 11 aldoses (maltose, xylose, arabinose, ribose, glucose ...
Yalong Lu +4 more
doaj +1 more source
d-Idose, d-Iduronic Acid, and d-Idonic Acid from d-Glucose via Seven-Carbon Sugars
Molecules, 2019 A practical synthesis of the very rare sugar d-idose and the stable building blocks for d-idose, d-iduronic, and d-idonic acids from ido-heptonic acid requires only isopropylidene protection, Shing silica gel-supported periodate cleavage of the C6-C7 ...
Zilei Liu +5 more
doaj +1 more source