Results 51 to 60 of about 5,891 (174)

Sequential catalytic nanosystem of carbon dots and uricase integrated with polydopamine for therapy of gouty wound ulceration

BMEMat, EarlyView.
Sequential dual‐catalytic treatment of the gout wound ulceration process by CDs‐Uri@PDA. (a) Synthesis steps and morphology of CDs‐Uri@PDA. (b) Sequential treatment process and mechanism of CDs‐Uri@PDA for gout wound ulceration according to (i) uric acid reduction, (ii) antibacterial activity, and (iii) anti‐inflammatory effects.
Yonglan Yang, Yang Yang, Pengpeng Ma, Ruiqi Zhu, Xia Pan, Shaoling Zheng, Bo Chen, Yanli Jin, Youcong Gong, Jie Liu, Tianwang Li, Xu Chen   +11 more
wiley   +1 more source

Engagement of CD14 Mediates the Inflammatory Potential of Monosodium Urate Crystals [PDF]

The Journal of Immunology, 2006
Abstract Phagocyte ingestion of monosodium urate (MSU) crystals can induce proinflammatory responses and trigger acute gouty inflammation. Alternatively, the uptake of MSU crystals by mature macrophages can be noninflammatory and promote resolution of gouty inflammation.
Peter, Scott, Hong, Ma, Suganya, Viriyakosol, Robert, Terkeltaub, Ru, Liu-Bryan   +4 more
openaire   +2 more sources

Evaluation of Turmeric Nanoparticles as Anti-Gout Agent: Modernization of a Traditional Drug

Medicina, 2019
Background and objectives: Turmeric has assisted in the control of inflammation and pain for decades and has been used in combination with other nutraceuticals to treat acute and chronic osteoarthritis pain.
Mubin Mustafa Kiyani, Muhammad Farhan Sohail, Gul Shahnaz, Hamza Rehman, Muhammad Furqan Akhtar, Irum Nawaz, Tariq Mahmood, Mobina Manzoor, Syed Ali Imran Bokhari   +8 more
doaj   +1 more source

Gout in pregnancy: Obstetric and neonatal outcomes

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 349-355, April 2025.
Abstract Objective The pregnancy, delivery, and neonatal outcomes of pregnancies complicated by gout have yet to be evaluated in a population‐based study. We sought to evaluate the obstetric and neonatal outcomes in pregnant patients with gout using a national population database.
Sam Amar, Ahmad Badeghiesh, Haitham Baghlaf, Michael H. Dahan   +3 more
wiley   +1 more source

Monosodium urate crystals exposure is associated with limited transcriptional changes in primary human PBMCs

Romanian Journal of Internal Medicine
Monosodium urate (MSU) crystals are the primary cause of gout, however the knowledge on MSU crystals exposure and inflammatory changes found in immune cells is diverse, with reports ranging from very limited inflammatory effects to substantial ...
Nica Valentin, Badii Medeea, Gaal Orsolya, Cabău Georgiana, Cleophas Maartje, Naidu Akshayata, Hotea Ioana, , Jansen Tim L., Pamfil Cristina, Rednic Simona, Popp Radu A., Li Yang, Crișan Tania O., Joosten Leo A.B.   +14 more
doaj   +1 more source

Ultrasound Findings in Symptomatic HADD of the Hand and Wrist. A Case Series of 37 Patients

Journal of Clinical Ultrasound, EarlyView.
Ultrasound enables accurate diagnosis of hydroxyapatite deposition disease of the hand and wrist in patients with acute, non‐traumatic pain, typically in middle‐aged women. Characteristic calcifications, often in the resorptive phase, support diagnosis, while radiography may confirm findings without the need for advanced imaging.
Marco Becciolini, Riccardo Picasso, Antonio Corvino, Federico Zaottini   +3 more
wiley   +1 more source

The Role of Inhibitory Receptors in Monosodium Urate Crystal-Induced Inflammation [PDF]

Frontiers in Immunology, 2018
Inhibitory receptors are key regulators of immune responses. Aberrant inhibitory receptor function can either lead to an exacerbated or defective immune response. Several regulatory mechanisms involved in the inflammatory reaction induced by monosodium urate crystals (MSU) during acute gout have been identified.
Maria J. Fernandes, Paul H. Naccache
openaire   +3 more sources

Effects of catechins, resveratrol, silymarin components and some of their conjugates on xanthine oxidase‐catalyzed xanthine and 6‐mercaptopurine oxidation

Journal of the Science of Food and Agriculture, Volume 105, Issue 5, Page 2765-2776, 30 March 2025.
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Tímea Bencsik, Orsolya Balázs, Róbert G Vida, Balázs Z Zsidó, Csaba Hetényi, Kateřina Valentová, Miklós Poór   +6 more
wiley   +1 more source

In-vitro crystallization of spherulites of monosodium urate monohydrate

Journal of Materials Science: Materials in Medicine, 1995
Sherulitic and an aggregate of bow shaped crystals of monosodium urate monohydrate which had a close resemblance to that of those crystals found in gouty synovial fluids and articular cartilage have been grown using tetramethoxysilane and silica gel.
S. Narayana Kalkura, E. K. Girija, M. Kanakavel, P. Ramasamy   +3 more
openaire   +1 more source

Macrophage Recognition of Crystals and Nanoparticles

Frontiers in Immunology, 2018
Inhalation of exogenous crystals such as silica, asbestos, and carbon nanotubes can cause lung fibrosis and cancer. Endogenous crystals such as monosodium urate, cholesterol, and hydroxyapatite are associated with pathogenesis of gout, atherosclerosis ...
Masafumi Nakayama, Masafumi Nakayama
doaj   +1 more source