Results 31 to 40 of about 16,282 (252)

Saturated free fatty acids induce placental trophoblast lipoapoptosis.

PLoS ONE, 2021
IntroductionObesity during pregnancy increases the risk for maternal complications like gestational diabetes, preeclampsia, and maternal inflammation. Maternal obesity also increases the risk of childhood obesity, intrauterine growth restriction (IUGR ...
Sathish Kumar Natarajan, Taylor Bruett, Philma Glora Muthuraj, Prakash K Sahoo, Jillian Power, Justin L Mott, Corrine Hanson, Ann Anderson-Berry   +7 more
doaj   +1 more source

Monounsaturated fatty acids and immune function [PDF]

European Journal of Clinical Nutrition, 2002
Animal studies generally support the idea that olive oil, rich in oleic acid, is capable of modulating functions of cells of the immune system. Importantly, several studies have demonstrated suppressive effects of oleic acid-containing diets on in vivo immune responses.
openaire   +2 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Phytosterols partially explain differences in cholesterol metabolism caused by corn or olive oil feeding

Journal of Lipid Research, 1998
To examine whether phytosterols in polyunsaturated oils account for their differential action on lipid metabolism compared with monounsaturated oils, 16 normolipidemic individuals consumed three 10-day experimental diets containing corn oil (high in ...
Tanya J. Howell, Diane E. MacDougall, Peter J.H. Jones   +2 more
doaj   +1 more source

Effect of animal and industrial trans fatty acids on HDL and LDL cholesterol levels in humans - a quantitative review [PDF]

, 2010
Background: Trans fatty acids are produced either by industrial hydrogenation or by biohydrogenation in the rumens of cows and sheep. Industrial trans fatty acids lower HDL cholesterol, raise LDL cholesterol, and increase the risk of coronary heart ...
Wanders Anne J., Brouwer, I.A.; id_orcid, Martijn B. Katan, Katan Martijn B., Martijn B Katan, Ingeborg A Brouwer, Anne J. Wanders, Brouwer, I.A., Katan, M.B.; id_orcid, Katan, M.B., Anne J Wanders, Wanders, A.J., Ingeborg A. Brouwer, Brouwer Ingeborg A.   +13 more
core   +1 more source

CEBPG‐Mediated Palmitic Acid Adaptation of Cancer‐Associated Fibroblasts Drives Metastasis of Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study reveals a metabolic signaling axis in the OSCC microenvironment where palmitic acid (PA) drives the activation of CAFs. PA uptake triggers CEBPG‐dependent epigenetic remodeling to upregulate ERN1 and TMBIM6, thereby mitigating ER stress. This adaptive program sustains CAF survival and the pro‐metastatic phenotype, establishing this pathway ...
Yiling Duan, Yitong Li, Yufei Wu, Xiao Yang, Rui Li, Hui Zhao, Zhengjun Shang   +6 more
wiley   +1 more source

Electron ionization mass fragmentation of monounsaturated long-chain alpha,omega-dicarboxylic acid trimethylsilyl derivatives.

, 2022
RATIONALELong-chain monounsaturated -dicarboxylic acids are important components of the cuticle and suberized cell walls of plants.Identification and quantification of these compounds, which are widespread in environmental samples, can be challenging ...
Claude Aubert, Rontani, Jean-Francois, Daubert, Claude, Jean‐François Rontani, Aubert, Claude   +4 more
core   +1 more source

PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression

Advanced Science, EarlyView.
Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian, Yifan Cheng, Jiajie Zhou, Ruiqi Li, Shuai Zhao, Ben Li, Zijie Xu, Mengli Zi, Yayan Fu, Chenkai Zhang, Qiannan Sun, Shantanu Baral, Sen Wang, Daorong Wang   +13 more
wiley   +1 more source

The Role of Stearoyl-coenzyme A Desaturase 1 in Liver Development, Function, and Pathogenesis

Journal of Renal and Hepatic Disorders, 2019
Stearoyl-coenzyme A desaturase 1 (SCD1) is a microsomal enzyme that controls fatty acid metabolism and is highly expressed in hepatocytes. SCD1 may play a key role in liver development and hepatic lipid homeostasis through promoting monounsaturated ...
Fatemeh Mohammadzadeh, Vahid Hosseini, Alireza Alihemmati, Amir Mehdizadeh, Maghsod Shaaker, Gholamali Mosayyebi, Masoud Darabi   +6 more
doaj   +1 more source

Soybean Lipoxygenase-Mediated Oxygenation of Monounsaturated Fatty Acids to Enones

, 2016
Soybean Lipoxygenase-Mediated Oxygenation of Monounsaturated Fatty Acids to ...
Charles H. Clapp (2514169), Thomas C. Potter (2983128), Theodore J. Stover (2983125), Peter M. Findeis (1346622), Susan E. Senchak (2983122), Mark J. Novak (2418607)   +5 more
core   +1 more source