Results 141 to 150 of about 24,480 (215)

High temporal resolution monitoring of illicit drug consumption across England via wastewater analysis

open access: yesAddiction, Volume 121, Issue 8, Page 2043-2059, August 2026.
Abstract Aim To monitor community‐level consumption of 20 illicit drugs across urban areas of England using wastewater‐based epidemiology (WBE) surveillance at high temporal resolution. Design, setting, cases This study was conducted over a 12‐month period in 2022 sampling 24‐hour composite wastewater samples at 15 wastewater treatment plants (WWTPs ...
Helena Rapp‐Wright   +14 more
wiley   +1 more source

Decoding kratom: molecular mechanisms and epigenetic factors in use and dependence. [PDF]

open access: yesTransl Psychiatry
Misnan E   +4 more
europepmc   +1 more source

The Opioid Safety Toolkit: An interactive prescription opioid safety toolkit to increase opioid safety literacy and behaviours among people prescribed opioids for pain—a randomised controlled trial

open access: yesAddiction, Volume 121, Issue 8, Page 2071-2082, August 2026.
Abstract Background and aims Prescription opioid‐related harm remains a significant public health concern. This study aimed to evaluate the efficacy of the Opioid Safety Toolkit, a co‐designed, interactive online resource, in increasing naloxone uptake and healthcare provider discussions among adults prescribed opioids for pain.
Suzanne Nielsen   +13 more
wiley   +1 more source

Patient‐reported outcomes, postoperative pain and pain relief after day‐case surgery (POPPY): short‐term peri‐operative analgesic use

open access: yesAnaesthesia, Volume 81, Issue 8, Page 1057-1067, August 2026.
Summary Introduction An increasing proportion of complex surgical procedures are being performed in the UK as day‐cases, with variable and limited follow up. Discharge prescriptions must provide adequate analgesia, while considering the safety of the patient and public, following best practice guidance and good opioid stewardship.
Anna Ratcliffe   +2083 more
wiley   +1 more source

CoolCuddle and Autonomic Regulation in Infants With Hypoxic‐Ischaemic Encephalopathy: An Intervention Study

open access: yesActa Paediatrica, Volume 115, Issue 8, Page 1688-1699, August 2026.
ABSTRACT Aim We evaluated the impact of ‘CoolCuddle’, parental cuddling during therapeutic hypothermia intervention for hypoxic‐ischaemic encephalopathy, on heart rate variability (HRV). Methods In this prospective, single‐group, interventional study with repeated measures, we included infants ≥ 36 weeks' gestation undergoing hypothermia and CoolCuddle
Ela Chakkarapani   +3 more
wiley   +1 more source

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