Results 41 to 50 of about 10,950 (303)

Highly Sensitive In-Capillary Derivatization and Field Amplified Sample Stacking to Analyze Narcotic Drugs in Human Serum by Capillary Zone Electrophoresis

open access: yesSeparations, 2023
An in-capillary derivatization (in-CAP-D) integrated with field amplified sample stacking (FASS) has been developed for the determination of morphine (MOR) and its metabolite, morphine-6-glucuronide (MOR-6-G) in human serum using capillary zone ...
Monika Malak   +6 more
doaj   +1 more source

Efficacy of Local Bupivacaine Injection of Postoperative Pain in Endoscopic Sinus Surgery

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Regional anesthesia is effective in alleviating postoperative pain and reducing the requirement for systemic pain medications. However, optimal postoperative pain management in endoscopic sinus surgery (ESS) remains challenging.
Wiracha Leewannapasai   +4 more
wiley   +1 more source

The Prevalence Rate of Substance Abuse in Applicants for Marriage in Isfahan Province, Iran, from 2013 to 2017

open access: yesمجله دانشکده پزشکی اصفهان, 2020
Background: Applicants for marriage in Iran must undergo mandatory screening tests for substance abuse before the wedding. The aim of this study was to determine the prevalence rate of substance abuse in applicants for marriage in Isfahan Province from ...
Reza Khadivi   +2 more
doaj   +1 more source

The persistence of chronic opioid use in patients with inflammatory bowel disease—A nationwide cohort study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Pain is common in patients with Crohn's disease (CD) and ulcerative colitis (UC), and a substantial proportion develop chronic opioid use (COU). We examined the persistence of COU over time and identified factors predicting persistent use. Methods This nationwide Danish cohort study included patients with an initial period of COU (definition: ≥3 ...
Bente Mertz Nørgård   +6 more
wiley   +1 more source

Antinociceptive and Cytotoxic Activity of Opioid Peptides with Hydrazone and Hydrazide Moieties at the C-Terminus

open access: yesMolecules, 2020
In the present contribution, we analyze the influence that C-terminal extension of short opioid peptide sequences by organic fragments has on receptor affinity, in vivo analgesic activity, and antimelanoma properties.
Jolanta Dyniewicz   +5 more
doaj   +1 more source

Drug poisonings following bariatric surgery: Case series report

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Bariatric surgery alters gastrointestinal anatomy and physiology, which likely impacts upon oral medication absorption. Drug‐ and alcohol‐related deaths in this population are being increasingly reported; however, toxicological detail is lacking. Using data reported to the National Programme on Substance Use Mortality, we identified 18 deaths in people
Eman Mshari   +3 more
wiley   +1 more source

Unusual fetal ascites and spontaneous bladder rupture in a female fetus: a case report

open access: yesJournal of Medical Case Reports, 2020
Background Fetal bladder rupture causing urinary ascites is uncommon. It is generally related to invasive fetal medicine procedures or obstructive disorders such as in posterior urethral valves in male fetuses.
Florence Cadoret   +6 more
doaj   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale   +5 more
wiley   +1 more source

Quantification of morphine in exhaled breath condensate using a double network polymeric hybrid hydrogel functionalized with AuNPs

open access: yesBMC Chemistry
Background Morphine serves as a foundation for creating other opioid derivatives, such as hydro/oxymorphine and heroin, which possess enhanced pain-relieving properties but are also prone to addiction and abuse. In cases of morphine overdose, it not only
Zahra Karimzadeh   +4 more
doaj   +1 more source

Sentience in cephalopod molluscs: an updated assessment

open access: yesBiological Reviews, EarlyView.
ABSTRACT This article evaluates the evidence for sentience – the capacity to have feelings – in cephalopod molluscs: octopus, cuttlefish, squid, and nautilus. Our framework includes eight criteria, covering both whether the animal's nervous system could support sentience and whether their behaviour indicates sentience.
Alexandra K. Schnell   +4 more
wiley   +1 more source

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