Results 141 to 150 of about 25,416 (201)

Morphine Withdrawal Dramatically Reduces Lymphocytes in Morphine-Dependent Macaques

Journal of Neuroimmune Pharmacology, 2006
The immune effects of chronic opiate exposure and/or opiate withdrawal are not well understood. The results of human studies with opiate abusers are variable and may not be able to control for important factors such as subjects' drug histories, health and nutritional status. Nonhuman primate models are necessary to control these important factors.
Michael R, Weed, Lucy M, Carruth, Robert J, Adams, Nancy A, Ator, Robert D, Hienz   +4 more
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Ultrasounds during morphine withdrawal in rats

Psychopharmacology, 1991
Ultrasounds (US) in rats may communicate affective states, as they occur only in highly significant situations such as maternal care, sex and aggression. Withdrawal from morphine is a manipulation which dramatically alters autonomic, somatic and motor functions; the present experiment demonstrated the production of US in this context and the influence ...
J A, Vivian, K A, Miczek
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Orphanin FQ/nociceptin inhibits morphine withdrawal

Life Sciences, 2000
The influence of orphanin FQ/nociceptin (OFQ/N) on the morphine-withdrawal symptom was investigated. Withdrawal syndrome was induced in the morphine-dependent rats by an intraperitoneal (i.p.) injection of 2 mg/kg naloxone hydrochloride--an opioid receptors antagonist. Wet-dog shakes were used as a measure of the abstinence syndrome.
J, Kotlińska, P, Suder, A, Legowska, K, Rolka, J, Silberring   +4 more
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Morphine-withdrawal aggression: Sensitization by amphetamines

Psychopharmacologia, 1971
Aggressive behaviors during the withdrawal from morphine sulfate (400 mg/kg/day), were potentiated by methylphenidate or d and l isomers of amphetamine. d-Amphetamine was most active, while hydroxyamphetamine was without any effect. Optimum effect of the drugs depended upon the drug dose and the time of morphine withdrawal.
H, Lal, J, O'Brien, S K, Puri
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Neurotransmitter Mechanisms of Morphine Withdrawal Syndrome

Bulletin of Experimental Biology and Medicine, 2009
Activity of the major neurotransmitter systems in the brainstem and cerebellum was studied in rats with morphine withdrawal syndrome. The most significant changes were found in the brainstem of animals by the 36th hour and 7 days after morphine withdrawal.
S V, Lelevich, V V, Lelevich, A A, Novokshonov   +2 more
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PSYCHOSIS DURING WITHDRAWAL OF MORPHINE

Archives of Neurology And Psychiatry, 1947
THE PSYCHOSES usually attributed to the use of morphine may be classified as follows: (1) chronic psychosis due to habitual use; (2) psychosis due to withdrawal; (3) psychosis due to idiosyncrasy to the drug. At the United States Public Health Service Hospital, Lexington, Ky., which is devoted primarily to the treatment of drug addiction, and where ...
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Morphine withdrawal, treatments 1900-30

History of Psychiatry, 1999
The treatments used between 1900 and 1930 for morphine withdrawal are discussed. The accounts are mainly taken from contemporary textbooks which contain fascinating descriptions of their authors' preferred methods and criticisms of regimes given by other therapists. Delirium, produced by atropine or similar substances, is advocated to cover withdrawal
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Petrosaspongiolide M reduces morphine withdrawal in vitro

Life Sciences, 2003
The bee venom phospholipase A(2) (PLA(2)) inhibitory activity of petrosaspongiolide M (PM), a marine metabolite displaying a potent anti-inflammatory activity and able to covalently bind and block group II and III secretory PLA(2) enzymes, has been investigated by mass spectrometry and molecular modeling. The model reveals interesting insight on the PM-
CAPASSO, Anna, CASAPULLO, Agostino, RANDAZZO A., GOMEZ PALOMA L.   +3 more
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Morphine withdrawal modifies antinociceptive effects of acute morphine in rats

Biochemical and Biophysical Research Communications, 2006
Repeated opioid use is known to cause tolerance of antinociceptive effects. Whether opioid abstinence modifies antinociceptive effects is unknown. Here we reported that morphine withdrawal for 18 h and 4 days after repeated morphine treatment largely reduced tail-flick latencies compared with control, while the rats showed severe withdrawal syndromes ...
Zhifang, Dong, Rongrong, Mao, Huili, Han, Jun, Cao, Lin, Xu   +4 more
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Voluntary morphine ingestion, morphine dependence, and recovery from withdrawal signs

Pharmacology Biochemistry and Behavior, 1975
We are reporting on conditions (without forced drinking or premedications) where rats voluntarily drink high quantities of sucrose-morphine solutions in preference to water. The volume ingested is inversely related to the morphine concentration in the liquid. The morphine antagonist, nalorphine, produced a clear set of opiate withdrawal signs in these (
K A, Khavari, T C, Peters, P L, Baity, A S, Wilson   +3 more
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