Results 131 to 140 of about 26,051 (190)

Alteration of morphine withdrawal to naloxone by interferon

Neuropeptides, 1983
The opiate abstinence syndrome represents a fundamental feature of the addictive process. The present study demonstrated that: 1) recombinant leukocyte A Interferon (alpha-IFN) injection prior to chronic morphine treatment reduces addiction liability; and 2) alpha-IFN and not human gamma-IFN injection to morphine dependent rats significantly modifies ...
N, Dafny, M, Zielinksi, C, Reyes-Vazquez
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Morphine suppression of ethanol withdrawal in mice

Experientia, 1976
The acute administration of morphine, alcohol or dopamine results in a pronounced suppression of the convulsions produced by alcohol in mice. The suppressive action of morphine on alcohol withdrawal in the mouse apparently is not a product of morphine intoxication, but rather to some other specific interaction between alcohol and morphine in the ...
K, Blum, J E, Wallace, H A, Schwerter, J D, Eubanks   +3 more
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Modification of morphine withdrawal by interferon

Life Sciences, 1983
Abstract Naloxone was administered to morphine dependent rats to elicit the opioid abstinence syndrome. Recombinant leukocyte A interferon treatment one hour prior to naloxone injection eliminated almost all of the abstinence behavioral signs observed.
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Conditioned morphine withdrawal in the hamster

Psychopharmacology, 1992
Conditioned withdrawal among golden Syrian hamsters was studied in two experiments. In experiment 1, morphine-pelleted (75 mg) hamsters were observed for signs of withdrawal (wet-dog shakes, etc.) before and after a naloxone (1 mg/kg) injection that was administered in a distinctive environment.
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Neurotransmitter Mechanisms of Morphine Withdrawal Syndrome

Bulletin of Experimental Biology and Medicine, 2009
Activity of the major neurotransmitter systems in the brainstem and cerebellum was studied in rats with morphine withdrawal syndrome. The most significant changes were found in the brainstem of animals by the 36th hour and 7 days after morphine withdrawal.
S V, Lelevich, V V, Lelevich, A A, Novokshonov   +2 more
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PSYCHOSIS DURING WITHDRAWAL OF MORPHINE

Archives of Neurology And Psychiatry, 1947
THE PSYCHOSES usually attributed to the use of morphine may be classified as follows: (1) chronic psychosis due to habitual use; (2) psychosis due to withdrawal; (3) psychosis due to idiosyncrasy to the drug. At the United States Public Health Service Hospital, Lexington, Ky., which is devoted primarily to the treatment of drug addiction, and where ...
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The Role of Dopamine in the Expression of Morphine Withdrawal

General Pharmacology: The Vascular System, 1998
1. Both L-dopa and low doses of apomorphine potentiated withdrawal symptoms such as jumping, "wet dog" shakes and burrows. L-dopa reduced hypothermia and potentiated body weight loss, whereas apomorphine produced opposite effects. 2. Higher doses of apomorphine attenuated jumping and burrows but had no effect on "wet dog" shakes. On the other hand, and
A O, el-Kadi, S I, Sharif
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Clonidine in Morphine Withdrawal

Archives of General Psychiatry, 1985
Reports of an antiwithdrawal effect for clonidine hydrochloride in acute opioid withdrawal are inconsonant with experimental findings that other nonopioids are ineffective. In the present investigation the antiwithdrawal effects of clonidine, morphine sulfate, and placebo were compared in volunteer addicts whose dependence was maintained by 15 mg of ...
D R, Jasinski, R E, Johnson, T R, Kocher
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Morphine-withdrawal aggression: Sensitization by amphetamines

Psychopharmacologia, 1971
Aggressive behaviors during the withdrawal from morphine sulfate (400 mg/kg/day), were potentiated by methylphenidate or d and l isomers of amphetamine. d-Amphetamine was most active, while hydroxyamphetamine was without any effect. Optimum effect of the drugs depended upon the drug dose and the time of morphine withdrawal.
H, Lal, J, O'Brien, S K, Puri
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Purinoreceptors are involved in the control of acute morphine withdrawal

Life Sciences, 2001
The effects exerted by P1 and P2 purinoceptor agonists and antagonists on the acute opiate withdrawal induced by morphine were investigated in vitro. Following a 4 min in vitro exposure to morphine, the guinea-pig isolated ileum exhibited a strong contracture after the addition of naloxone.
CAPASSO, Anna, A. LOIZZO
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