Results 111 to 120 of about 55,011 (233)

Pharmacological treatment strategies to manage precipitated withdrawal following the administration of buprenorphine in opioid use disorder: A systematic review

Addiction, Volume 121, Issue 5, Page 1083-1099, May 2026.
Abstract Background and aims There has been limited evidence synthesis examining the treatment of buprenorphine precipitated opioid withdrawal (BPOW). We aimed to conduct the first systematic review to assess the clinical utility of any pharmacological intervention in the management of BPOW.
Emmert Roberts, Nicola Kalk, John Strang
wiley   +1 more source

Brief report: Ketamine‐assisted “bridge therapy” for opioid tapering in complex cases

The American Journal on Addictions, Volume 35, Issue 3, Page 431-434, May 2026.
Abstract Background Opioid use disorder (OUD) presents major challenges, especially when combined with chronic pain and psychiatric comorbidities. A 25‐year‐old woman with OUD, chronic pain, and major depressive disorder underwent an 8‐week protocol of intravenous ketamine infusions (0.5 mg/kg weekly) as an adjunct to opioid tapering. Results Methadone
Mariana C. de Oliveira, Cláudia C. de Araujo Palmeira, André B. Negrão, Ziyad A. Hadi, Julia R. Arana, Rita de Cássia Ferreira Duarte, Joice L. P. da Silva, Gustavo K. Matsui, João F. D. Rapozero, Douglas H. Crispim, André Malbergier, João M. Castaldelli‐Maia   +11 more
wiley   +1 more source

Effect of Rosmarinus officinalis L. Aerial Parts Extract and Fractions on Morphine Withdrawal Syndrome in Mice

Journal of Medicinal Plants, 2006
Background: Our previous studies have shown that the aqueous and ethanolic extracts of Rosmarinus officinalis L. aerial parts reduce morphine withdrawal syndrome in mice. Objective: As R. officinalis L.
H Hosseinzadeh, M Ramezani, Sh Shahsavand   +2 more
doaj  

Divergence in μ and δ opioid receptor pharmacology in neurons and antinociceptive efficacy in neuropathic pain: Insights from MP135 and CYM51010

British Journal of Pharmacology, Volume 183, Issue 10, Page 2307-2323, May 2026.
Background and purpose Opioids targeting the μ opioid receptor remain largely ineffective in neuropathic pain conditions, emphasizing the need for novel therapeutic strategies. MP135 was reported to reduce thermal nociception in naive animals by activating μ‐δ opioid receptor heteromers.
Perrine Inquimbert, Chantal Fitterer, Sylvain Hugel, Mila Jesic, Yannick Goumon, Virgine Andry, Severine Schneider, Francois Daubeuf, Abdelfattah Faouzi, Stephane Doridot, Susruta Majumdar, Frederic Bihel, Martine Schmitt, Dominique Massotte   +13 more
wiley   +1 more source

Prenatal morphine exposure reduces pyramidal neurons in CA1, CA2 and CA3 subfields of mice hippocampus [PDF]

, 2014
Objective(s): This study was carried out to evaluate the effect of maternal morphine exposure during gestational and lactation period on pyramidal neurons of hippocampus in 18 and 32 day mice offspring.
Ghafari, S., Golalipour, M.J.
core   +1 more source

Prevalence and Patterns of Non‐Medical Gabapentinoid Use in a General Population Sample: Findings From the Australian National Drug Strategy Household Survey

Drug and Alcohol Review, Volume 45, Issue 4, May 2026.
ABSTRACT Introduction Gabapentinoid prescribing and related harms are increasing internationally, yet population‐level evidence on non‐medical use in Australia is lacking. This study estimated the prevalence and correlates of past‐year non‐medical gabapentinoid use and examined temporal trends. Methods Data were pooled from the 2016, 2019 and 2022–2023
Amy G. McNeilage, Ting Xia, Bridin Murnion, Claire E. Ashton‐James, Suzanne Nielsen   +4 more
wiley   +1 more source

Protracted opioid withdrawal behaviors are reduced by nitric oxide inhibition in mice

Addiction Neuroscience
Following opioid cessation, patients with opioid use disorder experience physical and psychological withdrawal symptoms. Prolonged negative affect, including anxiety and heightened stress reactivity, continues after physical withdrawal symptoms subside ...
Daniel J Kalamarides, Aditi Singh, John A Dani   +2 more
doaj   +1 more source

Nitrous Oxide: Mechanism of Its Antinociceptive Action [PDF]

, 1995
Nitrous oxide (N2O) is an anesthetic gas known to produce an analgesic effect at sub-anesthetic concentrations. This analgesic property of N2O can be clinically exploited in a broad range of conditions where pain relief is indicated.
Quock, Raymond M., Vaughn, Linda K.
core   +1 more source

Whole-Body Vibration Prevents Neuronal, Neurochemical, and Behavioral Effects of Morphine Withdrawal in a Rat Model. [PDF]

Int J Mol Sci, 2023
Jones GC, Small CA, Otteson DZ, Hafen CW, Breinholt JT, Flora PD, Burris MD, Sant DW, Ruchti TR, Yorgason JT, Steffensen SC, Bills KB.   +11 more
europepmc   +1 more source

Morphine Withdrawal-Induced Hyperalgesia in Models of Acute and Extended Withdrawal Is Attenuated by l-Tetrahydropalmatine. [PDF]

Int J Mol Sci, 2023
Oleinichenko D, Ahn S, Song R, Snutch TP, Phillips AG.   +4 more
europepmc   +1 more source