Results 121 to 130 of about 55,011 (233)

The Effect of Ethanol Extract of Aerial Parts of the Mentha piperita in the Acquisition, Tolerance Expression and Dependence to Morphine in Adult Male Mice

Armaghane Danesh Bimonthly Journal, 2015
Background & aim: Morphine dependence is a compulsive pattern of drug taking, resulting from the positive reinforcement of the rewarding effects of drug taking and the negative reinforcement of withdrawal syndrome that accompanies the cessation of drug ...
N Khajeh, A Eidi, J Zarringhalam
doaj  

Buprenorphine in Neonatal Abstinence Syndrome. [PDF]

, 2018
Infants exposed in utero to opioids will demonstrate a withdrawal syndrome known as neonatal abstinence syndrome (NAS). Buprenorphine is a long-acting opioid with therapeutic use in medication-assisted treatment of opioid dependency in adults and ...
Kraft, Walter K.
core   +1 more source

The cell-permeant antioxidant D-thiol ester D-cysteine ethyl ester overcomes physical dependence to morphine in male Sprague Dawley rats

Frontiers in Pharmacology
The ability of morphine to decrease cysteine transport into neurons by inhibition of excitatory amino acid transporter 3 (EAA3) may be a key molecular mechanism underlying the acquisition of physical and psychological dependence to morphine.
Paulina M. Getsy, Gregory A. Coffee, James N. Bates, Theodore Parran, Lee Hoffer, Santhosh M. Baby, Peter M. MacFarlane, Zackery T. Knauss, Derek S. Damron, Yee-Hsee Hsieh, Jason A. Bubier, Devin Mueller, Stephen J. Lewis, Stephen J. Lewis, Stephen J. Lewis   +14 more
doaj   +1 more source

Mitigating morphine dependence and withdrawal: The role of venlafaxine and calcium channel blockers in mitochondrial damage and oxidative stress in the brain

Brain Research Bulletin
Background: The reasons for morphine dependence and withdrawal symptoms are oxidative stress and dysfunction of cell mitochondria in the brain. Venlafaxine, a serotonin-norepinephrine reuptake inhibitor (SNRI), mitigates oxidative stress, while calcium ...
Radman Amiri, Faezeh Fallah, Behnam Ghorbanzadeh, Ali Akbar Oroojan, Mohammad Amin Behmanesh, Soheila Alboghobeish   +5 more
doaj   +1 more source

Kappa opioid receptor in nucleus accumbens regulates depressive-like behaviors following prolonged morphine withdrawal in mice. [PDF]

iScience, 2023
Zhang J, Lu Y, Jia M, Bai Y, Sun L, Dong Z, Tian W, Yin F, Wei S, Wang Y.   +9 more
europepmc   +1 more source

Carbamazepine potentiates morphine analgesia on postoperative pain in morphine-dependent rats [PDF]

, 2012
Postoperative pain and its control remain one of the most important issues in the field of surgery and health care systems. Morphine is a potent and effective analgesic, but substance abuse patients can manifest crosstolerance to it, making it ...
Moini Zanjani, Taraneh., Naseri, Kobra., Sabetkasaei, Masoumeh., Saghaei, Elham.   +3 more
core  

Loss of Astrocytic µ Opioid Receptors Exacerbates Aversion Associated with Morphine Withdrawal in Mice: Role of Mitochondrial Respiration. [PDF]

Cells, 2023
Murlanova K, Jouroukhin Y, Novototskaya-Vlasova K, Huseynov S, Pletnikova O, Morales MJ, Guan Y, Kamiya A, Bergles DE, Dietz DM, Pletnikov MV.   +10 more
europepmc   +1 more source

Placenta ingestion by rats enhances d- and k-opioid antinociception, but suppresses m-opioid antinociception [PDF]

, 2004
Ingestion of placenta or amniotic fluid produces a dramatic enhancement of centrally mediated opioid antinociception in the rat. The present experiments investigated the role of each opioid receptor type (m, d, k) in the antinociception-modulating ...
DiPirro, Jean M., Kristal, Dr. Mark B.
core  

Probing different paradigms of morphine withdrawal on sleep behavior in male and female C57BL/6J mice. [PDF]

Behav Brain Res, 2023
Bedard ML, Lord JS, Perez PJ, Bravo IM, Teklezghi AT, Tarantino LM, Diering GH, McElligott ZA.   +7 more
europepmc   +1 more source

Increased mRNA Expression for the α\u3csub\u3e1\u3c/sub\u3e Subunit of the GABA\u3csub\u3eA\u3c/sub\u3e Receptor Following Nitrous Oxide Exposure in Mice [PDF]

, 2001
The mechanisms by which nitrous oxide (N2O) produces physical dependence and withdrawal seizures are not well understood, but both N2O and ethanol exert some of their effects via the GABAA receptor and several lines of evidence indicate that withdrawal ...
Cullinan, William E., Johanek, Lisa M., Vaughn, Linda K.   +2 more
core   +1 more source