Results 141 to 150 of about 26,051 (190)
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Petrosaspongiolide M reduces morphine withdrawal in vitro
Life Sciences, 2003The bee venom phospholipase A(2) (PLA(2)) inhibitory activity of petrosaspongiolide M (PM), a marine metabolite displaying a potent anti-inflammatory activity and able to covalently bind and block group II and III secretory PLA(2) enzymes, has been investigated by mass spectrometry and molecular modeling. The model reveals interesting insight on the PM-
CAPASSO, Anna +3 more
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Morphine withdrawal modifies antinociceptive effects of acute morphine in rats
Biochemical and Biophysical Research Communications, 2006Repeated opioid use is known to cause tolerance of antinociceptive effects. Whether opioid abstinence modifies antinociceptive effects is unknown. Here we reported that morphine withdrawal for 18 h and 4 days after repeated morphine treatment largely reduced tail-flick latencies compared with control, while the rats showed severe withdrawal syndromes ...
Zhifang, Dong +4 more
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Catecholamine Metabolism in Morphine Withdrawal in the Dog
Nature, 1962I HAVE noted1 a decrease in the catecholamine content of the rat brain after withdrawal of chronic administration of morphine. This finding, however, seemed to be confined to a certain strain of rats with very conspicuous abstinence symptoms, while an increased urinary excretion of adrenaline and nor-adrenaline2 was observed in three different rat ...
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Morphine Withdrawal Dramatically Reduces Lymphocytes in Morphine-Dependent Macaques
Journal of Neuroimmune Pharmacology, 2006The immune effects of chronic opiate exposure and/or opiate withdrawal are not well understood. The results of human studies with opiate abusers are variable and may not be able to control for important factors such as subjects' drug histories, health and nutritional status. Nonhuman primate models are necessary to control these important factors.
Michael R, Weed +4 more
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Morphine withdrawal, treatments 1900-30
History of Psychiatry, 1999The treatments used between 1900 and 1930 for morphine withdrawal are discussed. The accounts are mainly taken from contemporary textbooks which contain fascinating descriptions of their authors' preferred methods and criticisms of regimes given by other therapists.
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Morphine withdrawal-facilitated aggression is attenuated by morphine-conditioned stimuli
Pharmacology Biochemistry and Behavior, 2001There is a considerable body of evidence indicating that stimuli associated with drug administration may become conditioned and evoke drug-like effects. The purpose of this study was to evaluate the ability of morphine-paired stimuli to affect an expression of morphine withdrawal-facilitated aggression.
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Pharmacological Cues, Morphine Tolerance, and Morphine Withdrawal
2003Results of many studies have demonstrated an important contribution of Pavlovian conditioning to the phenomena of drug tolerance and withdrawal. Based on the conditioning analysis, cues paired with the drug administration conditionally elicit compensatory responses in anticipation of the subsequent drug-induced physiological disturbance.
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Morphine Withdrawal in the Hamster
Annals of the New York Academy of Sciences, 1992openaire +2 more sources