Maternal substance use disorder and neonatal health: epidemiologic and socioeconomic determinants in a case-control study, Shiraz, Iran. [PDF]
Oboodi R +5 more
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Repeated naloxone-induced morphine withdrawal alters blood brain barrier and blood spinal cord barrier integrity in mice. [PDF]
Kohro Y, Brown CE, Trang T.
europepmc +1 more source
Proceedings: Jumping behavior as a withdrawal syndrome in morphinized rats.
H, Nakamura, Y, Yokoyama, M, Shimizu
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Hyperbaric oxygen treatment attenuates naloxone-precipitated opioid withdrawal behaviors and alters microglial activity in male and female mice. [PDF]
Southard MT +8 more
europepmc +1 more source
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Influence of ω-conotoxin on morphine analgesia and withdrawal syndrome in rats
European Journal of Pharmacology, 1992The effect of omega-conotoxin on opiate analgesia and withdrawal syndrome was investigated in rats. omega-Conotoxin given i.c.v. and i.p. caused weak analgesia in the tail-flick test. When the toxin (20 ng/rat) was given i.c.v. immediately before morphine (1.5 micrograms/rat i.c.v.) the resultant analgesic effect was additive.
Basilico L +4 more
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Neurotransmitter Mechanisms of Morphine Withdrawal Syndrome
Bulletin of Experimental Biology and Medicine, 2009Activity of the major neurotransmitter systems in the brainstem and cerebellum was studied in rats with morphine withdrawal syndrome. The most significant changes were found in the brainstem of animals by the 36th hour and 7 days after morphine withdrawal.
S V, Lelevich +2 more
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Clonidine suppresses methylxanthine induced quasi-morphine withdrawal syndrome
Pharmacology Biochemistry and Behavior, 1982The effects of the alpha-2 adrenergic agonist, clonidine, on the "quasi-morphine withdrawal syndrome" (QMWS) were examined in drug naive rats. The QMWS was induced by combined systemic administration of iso-butyl-methylxanthine (IBMX: 15 mg/kg, IP) and naloxone (1 mg/kg, IP).
S J, Grant, D E, Redmond
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We had previously found that co-injection of dextromethorphan, an antitussive drug and a non-competitive NMDA receptor antagonist, with morphine into dam rats throughout the pregnancy period could attenuate the naloxone-precipitated morphine withdrawal syndrome in their offspring.
Geng-Chang, Yeh +5 more
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Disulfiram attenuates morphine or methadone withdrawal syndrome in mice
Behavioural Pharmacology, 2018Taking opioids is often accompanied by the development of dependence. Unfortunately, treatment of opioid dependence is difficult, particularly because of codependence – for example, on alcohol or other drugs of abuse. In the presented study, we analyzed the potential influence of disulfiram, a drug used to aid the management of alcoholism, on opioid ...
Anna, de Cordé +5 more
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