Results 61 to 70 of about 1,336,492 (154)

Experimental study of the morphine de-addiction properties of Delphinium denudatum Wall.

BMC Complementary and Alternative Medicine, 2002
Background Our aim was to explore the de-addiction properties of Delphinium denudatum Wall. in morphine dependent rats. Methods Charles Foster male albino rats were made morphine dependent by injecting morphine sulphate in increasing doses twice a day ...
Kumar Anil, Ali Khan Rahat, Rahman Syed
doaj   +1 more source

Microinjection of Orexin-A into the Locus Coeruleus Area Induces Morphine Withdrawal Behaviors in Morphine Independent Rats

Research on Addiction, 2012
Introduction: Orexin neuropeptide has a role in opioid withdrawal behaviors. Orexin-expressing neurons that are present in the hypothalamic nuclei send dense projections to the Locus Coeruleus (LC).
Hosin Azizi, Atefeh Hadian, Saeed Semnanian   +2 more
doaj  

Amniotic-Fluid Ingestion Enhances\ud Morphine Analgesia During Morphine\ud Tolerance and Withdrawal in Rats [PDF]

, 1991
Ingestion of placenta and amniotic fluid has been shown to enhance opioid-mediated analgesia in rats produced by morphine injection. footshock, vaginal/cervical stimulation, and during late pregnancy.
Doerr, Jean C., Kristal, Dr. Mark B.
core  

The Effect of Ethanol Extract of Aerial Parts of the Mentha piperita in the Acquisition, Tolerance Expression and Dependence to Morphine in Adult Male Mice

Armaghane Danesh Bimonthly Journal, 2015
Background & aim: Morphine dependence is a compulsive pattern of drug taking, resulting from the positive reinforcement of the rewarding effects of drug taking and the negative reinforcement of withdrawal syndrome that accompanies the cessation of drug ...
N Khajeh, A Eidi, J Zarringhalam
doaj  

Effect of repeated morphine withdrawal on spatial learning, memory and serum cortisol level in mice

Advanced Biomedical Research, 2013
Background: One of the serious problems that opioid addicted people are facing is repeated withdrawal syndrome that is accompanying with a significant stress load for addicts.
Mahdieh Matinfar, Mahsa Masjedi Esfahani, Neda Aslany, Seyyed Hamid Reza Davoodi, Pouya Parsaei, Ghasem Zarei, Parham Reisi   +6 more
doaj   +1 more source

Mitigating morphine dependence and withdrawal: The role of venlafaxine and calcium channel blockers in mitochondrial damage and oxidative stress in the brain

Brain Research Bulletin
Background: The reasons for morphine dependence and withdrawal symptoms are oxidative stress and dysfunction of cell mitochondria in the brain. Venlafaxine, a serotonin-norepinephrine reuptake inhibitor (SNRI), mitigates oxidative stress, while calcium ...
Radman Amiri, Faezeh Fallah, Behnam Ghorbanzadeh, Ali Akbar Oroojan, Mohammad Amin Behmanesh, Soheila Alboghobeish   +5 more
doaj   +1 more source

The effect of eight weeks of moderate-intensity endurance training on some oxidant and antioxidant indices in testicular tissues of diabetic rats with acute morphine withdrawal syndrome [PDF]

مجله علوم پزشکی فیض (پیوسته)
Background and Aim: Diabetes, along with morphine, can lead to metabolic damage in testicular tissue through oxidative stress. This study aimed at investigating the effects of eight weeks of moderate-intensity endurance training on some oxidant and ...
Shahram Azarrang, Mohammad Parastesh, Abbas Saremi   +2 more
doaj  

Absence of quasi-morphine withdrawal syndrome in adenosine A2A receptor knockout mice

, 2012
Rationale: Caffeine and other methylxanthines induce behavioral activation and anxiety responses in mice via antagonist action at A2A adenosine receptors.
Cippitelli, Andrea, Granado, Noelia, Bilbao, Ainhoa, Bezard, Erwan, Rodríguez de Fonseca, Fernando, Martín- Hernández, A. B., Ortiz, Óscar, Moratalla, Rosario, Chen, Jiang-Fan, Navarro, Miguel   +9 more
core   +1 more source

An experimental therapy for opioid withdrawal syndrome

, 2023
The ongoing opioid crisis in the United States needs alternative therapeutics. To explore the role of the 5-HT2A serotonin receptor in opioid physical dependence and withdrawal syndrome, morphine dependent rats were treated with pimavanserin, a highly ...
Reed, Yvonne
core   +1 more source

Morphine withdrawal affects both delayed-escape behaviour in Morris water maze and hippocampal NR2A/2B expression ratio

, 2008
Repeated low-dose morphine treatment facilitates delayed-escape behaviour of hippocampus-dependent Morris water maze and morphine withdrawal influences hippocampal NMDA receptor-dependent synaptic plasticity.
Tian, Meng, Han, Huili, Xu, Tianle, Luo, Jianhong, Lin Xua, Mao, Rongrong, Sui, Nan, Xu, Lin, Dong, Zhifang, Zhong, Weixia, Cao, Jun   +10 more
core   +1 more source