Results 111 to 120 of about 567,251 (277)

Inhaled Angiopoietin‐Like 4 Antisense Oligonucleotide Therapy for Lung Injury and Fibrosis

Advanced Science, EarlyView.
Inhaled antisense oligonucleotides targeting ANGPTL4 attenuate inflammation, preserve barrier integrity, and reduce fibrosis in both infectious and sterile lung injury models. Integrated transcriptomic analysis reveals a conserved ANGPTL4‐regulated gene network coordinating hypoxic, inflammatory, apoptotic, and stress‐response pathways.
Haiyang Fan, Yuanyang Tan, Junhang Zhang, Xiaoya Liu, Jing Qu, Damien Chua, Hong Sheng Cheng, Joseph Han Sol Kim, Yu Xuan Liu, Changfei Qin, Yingzi Liu, Dezhi Li, Jikang Qiu, Mengshi Chi, Mingmin Bi, Qiwei Zhang, Yun Li, Masoumeh Motamedi Joibari, Stefan K Nilsson, Nguan Soon Tan, Yunping Fan, Liang Li   +21 more
wiley   +1 more source

UV-Vis and CIELAB Based Chemometric Characterization of Manihot esculenta Carotenoid Contents

Journal of Integrative Bioinformatics, 2017
Vitamin A deficiency is a prevalent health problem in many areas of the world, where cassava genotypes with high pro-vitamin A content have been identified as a strategy to address this issue.
Afonso Telma, Moresco Rodolfo, Uarrota Virgilio G., Navarro Bruno Bachiega, Nunes Eduardo da C., Maraschin Marcelo, Rocha Miguel   +6 more
doaj   +1 more source

Pattern of fin rays along the antero-posterior axis based on their connection to distal radials

Zoological Letters, 2019
Background Teleost paired fins are composed of two endoskeletal domains, proximal and distal radials, and an exoskeletal domain, the fin ray. The zebrafish pectoral fin displays elaborately patterned radials along the anteroposterior (AP) axis.
Hiroki Hamada, Toshiaki Uemoto, Yoshitaka Tanaka, Yuki Honda, Keiichi Kitajima, Tetsuya Umeda, Atsushi Kawakami, Minori Shinya, Koichi Kawakami, Koji Tamura, Gembu Abe   +10 more
doaj   +1 more source

Characterisation of inflorescence development in Zea mays with four developmental mutants : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biological Science at Massey University, Palmerston North, New Zealand [PDF]

, 2000
The genetic control of inflorescence development has been studied in great detail in the model dicotyledonous plants Arabidopsis thaliana and Antirrhinum majus. In contrast, little is known about the genetic regulation in monocotyledonous species.
Brown, Murray
core  

Indole‐3‐Propionic Acid Improves Alveolar Development Impairment via Targeting VAMP8‐mediated SNAREs Complex Formation in Bronchopulmonary Dysplasia

Advanced Science, EarlyView.
This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang, Xu Chen, Haowei Xu, Zhiqi Zeng, Keyu Lu, Yu Mao, Qianru Lv, Hui Shi, Song Liu, Xian Shen, Chunyu Yin, Yang Yang, Yan Guo, Xingyun Wang, Rui Cheng   +14 more
wiley   +1 more source

Robustness of force and stress inference in an epithelial tissue

, 2014
During morphogenesis, the shape of a tissue emerges from collective cellular behaviors, which are in part regulated by mechanical and biochemical interactions between cells.
Bellaïche, Y., Graner, F., Ishihara, S., Marcq, P., Sugimura, K.   +4 more
core   +1 more source

Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression

Advanced Science, EarlyView.
Mechanisms of Bufalin‐Mediated Intervention in Breast Cancer. ABSTRACT Breast cancer incidence is rising globally, presenting challenges such as treatment side effects and drug resistance. Bufalin is a bufadienolides compound with potential anti‐cancer effects. This study shows that bufalin inhibits malignant proliferation of MDA‐MB‐231 and MCF‐7 cells
Siyu Guo, Xiaodong Chen, Haojia Wang, Jiying Zhou, Peiying Lu, Jiangying Liu, Keyan Chai, Jingyuan Zhang, Siyun Yang, Shan Lu, Yifei Gao, Zhengsen Jin, Xiaoyu Tao, Zhongdong Hu, Qinglin Li, Jiarui Wu   +15 more
wiley   +1 more source

Engineered Living Systems With Self‐Organizing Neural Networks: From Anatomy to Behavior and Gene Expression

Advanced Science, EarlyView.
Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat, Laurie O'Neill, Léo Pio‐Lopez, Megan M. Sperry, Patrick Erickson, Tiffany Lin, Michael Levin   +6 more
wiley   +1 more source

Genome-wide identification of thyroid hormone receptor targets in the remodeling intestine during Xenopus tropicalis metamorphosis

Scientific Reports, 2017
Thyroid hormone (T3) affects development and metabolism in vertebrates. We have been studying intestinal remodeling during T3-dependent Xenopus metamorphosis as a model for organ maturation and formation of adult organ-specific stem cells during ...
Liezhen Fu, Biswajit Das, Kazuo Matsuura, Kenta Fujimoto, Rachel A. Heimeier, Yun-Bo Shi   +5 more
doaj   +1 more source

Topological Theory in Bioconstructivism [PDF]

, 2012
In the essay “Landscapes of Change: Boccioni’s Stati d’animo as a General Theory of Models,” in Assemblage 19, 1992, Sanford Kwinter proposed a number of theoretical models which could be applied to computer-generated forms in Bioconstructivism.
Hendrix, John S
core   +1 more source