Results 41 to 50 of about 23,743 (176)
Inorganics, 2023 The treatment of N-Phenylmorpholine-4-carbothioamide (HPMCT) with bivalent metal ions in a 2:1 mol ratio without a base present affords [MCl2(κ1S-HPMCT)2] {M = Cu(1), Pd(2), Pt(3), and Hg(4)} in a good yield.
Ahmed T. F. Al-Halbosy +7 more
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4-(4-Nitrophenyl)morpholine [PDF]
Acta Crystallographica Section E Structure Reports Online, 2012 Aromatic π–π stacking interactions stabilize the crystal structure of the title compound, C10H12N2O3, the perpendicular distance between parallel planes being 3.7721 (8) Å. The morpholine ring adopts a chair comformation.
Li-Jiao Wang +3 more
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Angewandte Chemie, EarlyView.Bei der Suche nach neuen allosterischen Stellen in der Serin/Threonin‐Kinase p38α deckt die NMR‐Spektroskopie eine dynamische Kopplung zwischen dem katalytischen Zentrum und der Lipidtasche auf. Die Ergebnisse offenbaren bewegungsbezogene Interdependenzen, die entfernte Regionen des Enzyms miteinander verbinden, was die Lipidtasche als ...
Sara Medina Gómez +4 more
wiley +1 more source
Frontiers in ChemistryIntroductionCancer is a complex group of diseases characterized by the uncontrolled growth and spread of abnormal cells in the body. These cells can invade nearby tissues and organs, or they may metastasize to other parts of the body through the ...
Elaheh Ataollahi +10 more
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Molecules, 2022 The α-glucosidase enzyme, located in the brush border of the small intestine, is responsible for overall glycemic control in the body. It hydrolyses the 1,4-linkage in the carbohydrates to form blood-absorbable monosaccharides that ultimately increase ...
Imran Ahmad Khan +6 more
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2-Deoxystreptamine Conjugates by Truncation–Derivatization of Neomycin
Pharmaceuticals, 2010 A small library of truncated neomycin-conjugates is prepared by consecutive removal of 2,6-diaminoglucose rings, oxidation-reductive amination of ribose, oxidation-conjugation of aminopyridine/aminoquinoline and finally dimerization.
Floris L. van Delft +5 more
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Sulfonamides with Heterocyclic Periphery as Antiviral Agents
Molecules, 2022 Sulfonamides are the basic motifs for a whole generation of drugs from a large group of antibiotics. Currently, research in the field of the new sulfonamide synthesis has received a “second wind”, due to the increase in the synthetic capabilities of ...
Mikhail Yu. Moskalik
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Zeitschrift für Naturforschung B, 1971 Cyclodehydrohalogenation-beta-Lactams-Morpholin-3-ones-H'-NMR Spectroscopy N-Aryl-N-chloroacetyl-2-chlorophenacylamines (2) give morpholinones 3, or beta-lactams 4, depending upon the N-aryl-substituent. N-Phenyl-N- (2,3-dibromo-3-phenylpropionyl) -4-nitrophenacylamine did not undergo base-catalysed cyclization but gave, instead, the α,β-
Riaz F. Abdulla, Alok N. Bannerji
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2-[(E)-(Morpholin-4-ylimino)methyl]-6-(morpholin-4-ylmethyl)phenol [PDF]
Acta Crystallographica Section E Structure Reports Online, 2013 The title compound, C16H23N3O3, contains two morpholine rings, each of which adopts a chair conformation. The mol-ecular conformation is stabilized by an intra-molecular O-H⋯N hydrogen bond, leading to a S(6) ring. In the crystal, mol-ecules are linked into zigzag chains along the c-axis direction by C-H⋯O and C-H⋯π inter-actions.
Akkurt M. +4 more
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Zeitschrift für Naturforschung B, 1970 ω- (N-aryl-chloracetamido) -acetophenones have been cyclized with triethylamine in warm benzene solution to the corresponding 1,4-oxazines. The reaction appears to be general for any N-aryl substituent, as long as an overall electron-withdrawing substituent is present para- or meta, in the aromatic nucleus of the acetophenone moiety.
Basanta G. Chatterjee, Riaz F. Abdulla
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