Results 71 to 80 of about 44,228 (262)

Pharmaceuticals Made with Hydrogen: A Sustainable and Efficient Approach Using Flow Synthesis

Chemistry – A European Journal, EarlyView.
We demonstrate a sustainable strategy for pharmaceutical manufacturing by combining hydrogen, heterogeneous catalysis, and continuous flow synthesis. The development of novel catalysts and their application in a multi‐step synthesis of donepezil enabled a highly productive process with no intermediate purification.
Shū Kobayashi, Haruro Ishitani
wiley   +1 more source

Morpholines-(I)

Zeitschrift für Naturforschung B, 1970
ω- (N-aryl-chloracetamido) -acetophenones have been cyclized with triethylamine in warm benzene solution to the corresponding 1,4-oxazines. The reaction appears to be general for any N-aryl substituent, as long as an overall electron-withdrawing substituent is present para- or meta, in the aromatic nucleus of the acetophenone moiety.
Basanta G. Chatterjee, Riaz F. Abdulla
openaire   +1 more source

Late‐Stage Phenylation From [13C6] and [2H5]Benzene: A Versatile Tool for Stable Isotope Labeled MS Standards

Chemistry – A European Journal, EarlyView.
ABSTRACT We explored aryl thianthrenation as a tool for directly incorporating multiple isotopes into molecular scaffolds starting from full isotopically labeled benzene. Stable isotope‐labeled (SIL) molecules are indispensable tools for investigating chemical and biological mechanisms and quantifying metabolites.
Alexandre Labiche, Bouchaib Mouhsine, Dorian Dupommier, Louise Fogel, Frédéric Robert, David‐Alexandre Buisson, Frédéric Taran, Davide Audisio   +7 more
wiley   +1 more source

Synthesis, Antifungal and Antitumor Activity of Novel (Z)-5-Hetarylmethylidene-1,3-thiazol-4-ones and (Z)-5-Ethylidene-1,3-thiazol-4-ones

Molecules, 2013
New hetaryl- and alkylidenerhodanine derivatives 3a–d, 3e, and 4a–d were prepared from heterocyclic aldehydes 1a–d or acetaldehyde 1e. The treatment of several rhodanine derivatives 3a–d and 3e with piperidine or morpholine in THF under reflux, afforded (
Susana A. Zacchino, Justo Cobo, María Victoria Rodríguez, Manuel Nogueras, Rodrigo Abonia, Jairo Quiroga, Carlos Echeverry, Marcela Raimondi, Juan Ramírez, Alberto Insuasty, Braulio Insuasty   +10 more
doaj   +1 more source

4,6-Diferrocenyl-5-(morpholin-4-yl)-1,2,3-triazine

IUCrData, 2023
The structure of the title Fe complex, [Fe(C5H5)2(C17H16N4O)], was determined at 130 K, and has orthorhombic (Pna21) symmetry. It is of interest with respect to the class of triazine heterocyclic compounds: the triazine ring is substituted by two ...
Carla Aguilar-Lugo, Marcos Flores-Alamo, Jessica J. Sánchez García, Elena I. Klimova   +3 more
doaj   +1 more source

Nanostructures from self-assembling triazine tertiary amine N-oxide amphiphiles [PDF]

, 2013
A new set of amphiphilic tertiary amine N-oxides has been prepared and their self-assembly properties observed in aqueous solution by tensiometry, dynamic and static light scattering.
Adamczyk, Albertorio, Ariga, Aswal, Barberá, Barlow, Baskakov, Baskakov, Baskakov, Bernier, Bolen, Cafferty, Chae, Chae, Chae, Chae, Chae, Chaudier, Cheng, Dabkowski, De, De Bernardez Clark, Diaz-Ortiz, Dilly, Goracci, Harries, Herrmann, Jorgensen, Kakehashi, Kameta, Kane, Kawasaki, Kawasaki, Kawasaki, Kawasaki, Kimizuka, Koopman, Kuwamura, Lair, Lewinska, Ma, Macdonald, Maeda, Maly, Marsh, Marsh, McQuade, Middelberg, Moore, Muraoka, Murray, Nowick, O’Neil, O’Neil, Rasmussen, Rasmussen, Rathman, Rosenbaum, Sagle, Simanek, Singh, Singh, Stanczak, Tao, Thorsteinsson, Vincentelli, Vuillard, Vuillard, Wang, Wuest, Yancey, Yu, Zhang, Zhang   +73 more
core   +1 more source

Potassium morpholine-4-carbodithioate monohydrate [PDF]

Acta Crystallographica Section E Structure Reports Online, 2012
In the ionic title compound, K+·C5H8NOS2−·H2O, the morpholine ring of the morpholine-4-carbodithioate anion has a chair conformation. The potassium cation is coordinated by four S and four O atoms in a bipyramidal reversed geometry. In the crystal, the three components are linked, generating infinite two-dimensional networks that lie parallel to ...
Ana C, Mafud, Maria Teresa Prado, Gambardella   +1 more
openaire   +3 more sources

Highly Potent Fluorogenic Ligands for Triplex DNA: 5‐Substituted 2‐(Naphthalen‐2‐yl)‐4H‐Chromen‐4‐Ones

Chemistry – A European Journal, EarlyView.
5‐Substituted 2‐(naphthalen‐2‐yl)‐4H‐chromen‐4‐ones are reported as a novel class of highly potent and selective triplex DNA ligands. These ligands induce triplex formation at submicromolar concentrations and inhibit enzymatic activity via ligand‐mediated triplex formation.
Nghia Tran, Landy Gu, Krege M. Christison, Kalee Thao, Liang Xue   +4 more
wiley   +1 more source

Method and device for detection of surface discontinuities or defects [PDF]

, 1974
Surface discontinuities of defects such as cracks and orifices are detected by applying a penetrating fluid, preferably a liquid, to a test surface so as to cause the liquid to penetrate any minute cracks or opening in the surface, removing the excess ...
Leger, L. J.
core   +1 more source

Core-substituted naphthalene diimides: influence of substituent conformation on strong visible absorption [PDF]

, 2017
Substitution of the aromatic core of naphthalene diimide (NDI) chromophores by morpholine leads to molecules with strong absorbance in the visible spectrum.
Al Kobaisi, Bhosale, Bhosale, Bhosale, Borgström, Chaignon, Chen, Dawson, Goretzki, Guha, Gunderson, Iengo, Jaggi, Jia, Kishore, Laquindanum, Llewellyn, Pan, Rananaware, Röger, Sakai, Schneebeli, Sommer, Suraru, Suseela, Zhan, Zhao   +26 more
core   +2 more sources