Results 121 to 130 of about 114,749 (302)
Forecasting life expectancy in São Paulo City, Brazil, amidst the COVID-19 pandemic
Population Health MetricsBackground The COVID-19 pandemic has significantly increased mortality rates, disrupting historical trends and making it challenging to forecast future life expectancy levels. São Paulo, the first city in Brazil to report a COVID-19 case and death, saw a
Maria L. Miranda +2 more
doaj +1 more source
A methodology for population projections: an application to Spain [PDF]
This paper looks at projections for the Spanish population by sex and age for the period of 2005 to 2050. These were carried out using forecasts for birth and mortality rates, and migration.
Andrés M. Alonso +2 more
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FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Lee-Carter mortality forecasting: a multi-country comparison of variants and extensions [PDF]
We compare the short- to medium-term accuracy of five variants or extensions of the Lee-Carter method for mortality forecasting. These include the original Lee-Carter, the Lee-Miller and Booth-Maindonald-Smith variants, and the more flexible Hyndman ...
Heather Booth +3 more
core +3 more sources
What do Bayesian methods offer population forecasters?
, 2010 The Bayesian approach has a number of attractive properties for probabilistic forecasting. In this paper, we apply Bayesian time series models to obtain future population estimates with uncertainty for England and Wales.
Abel, Guy J. +4 more
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FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Life Table Forecasting with the Gompertz Distribution [PDF]
, 2007 First, this paper investigates the properties of the Gompertz distribution and the relationships of their constants. Then the use of Gompertz´s law to describe mortality is discussed with male and female period life table data of the United States ...
Pflaumer, Peter
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FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
Why population forecasts should be probabilistic - illustrated by the case of Norway [PDF]
Deterministic population forecasts do not give an appropriate indication of forecast uncertainty. Forecasts should be probabilistic, rather than deterministic, so that their expected accuracy can be assessed.
Arve Hetland +2 more
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