Results 131 to 140 of about 33,949 (297)

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Using an Improved ARIMA Algorithm to Forecast the Cancer Mortality in Taiwan in the Next Five Years

, 2020
[[abstract]]The first cause of death in the elderly is also cancer, and unfortunately, the percentage of such death in people over 65 years old is increasing with days.
莊政宏;Chuang, Cheng-Hung;呂威甫;Lu, Wei-Fu;陳瑞奇;Chen, Jui-Chi
core  

Lee-Carter Cohort Mortality Forecasts

, 2022
Mortality forecasting has recently stimulated great interest in academics and financial sector practitioners due to the increasing challenges posed by continuous longevity improvements. Many efforts have been directed to model and forecast mortality from
Camarda, Carlo Giovanni, Basellini, Ugofilippo   +1 more
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Bayesian hierarchical multi-population mortality modelling for China's provinces

, 2019
China has experienced large improvements in mortality rates, but there remain substantial variations at the provincial level. This paper develops new models to project mortality at both the national and provincial levels in China.
Wang, Xiaojun, Lu, Qian, Hanewald, Katja ; https://orcid.org/   +2 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Personalized ICU mortality assessment by interpretable machine learning algorithms in patients with sepsis combined lung cancer: a population-based study and an external validation cohort

Frontiers in Oncology
PurposeSepsis is a leading cause of mortality, especially among immunocompromised patients with lung cancer. We aimed to establish machine learning (ML) based model to accurately forecast ICU mortality in patients with sepsis combined lung cancer ...
Hongjie Tang, Hairong Hao, Yue Han
doaj   +1 more source

Ethnic-wise population forecast for Singapore using Lee Carter model for mortality, fertility and migration.

, 2011
In this study, we investigate Singapore population using the variant of Lee-Carter model proposed by Hyndman and Ullah. The mortality rates, fertility rates and net migration numbers which form the basis of the population are analysed.
Low, Yik Hua., Goh, Siu Wei., Ong, Min Sion.   +2 more
core  

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Forecast of mortality rates in Colombia: an approach based on functional data analysis

, 2021
ilustraciones, gráficas, tablasEn este proyecto se recurre al análisis de datos funcionales con el fin de modelar y pronosticar curvas de mortalidad en Colombia, en particular, se hace uso de la metodología propuesta por Hyndman y Ullah en el año 2007 ...
Forero Orjuela, Raúl Alberto
core