Results 111 to 120 of about 114,749 (302)

Dynamics and forecast of morbidity and mortality from prostate cancer in St. Petersburg

open access: yesУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2015
The paper presents the characteristics of primary disease incidence, prevalence and mortality from prostate cancer among men's population of St. Petersburg (normal and age-standardized rates); analyzed their dynamics for 20 years; shows the calculated ...
N. G. Petrova   +2 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Forecasting sex differences in mortality in high income nations: The contribution of smoking

open access: yesDemographic Research, 2005
To address the question of whether the sex differential in mortality will in the future rise, fall, or stay the same, this study uses the relative smoking prevalence among males and females to forecast future changes in relative smoking-attributed ...
Fred Pampel
doaj  

Socio-economic status, sexual behavior, and differential AIDS mortality Evidence from Cˆote d’Ivoire [PDF]

open access: yes
Lack of knowledge about differential AIDS mortality seriously hampers the study of the economic impact of AIDS in developing countries, at both the macro and micro-economic levels.
Denis Cogneau, Michael Grimm
core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Forecasts of cohort mortality after age 50 [PDF]

open access: yes
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James W. Vaupel, Kirill F. Andreev
core  

Identifiability issues of age-period and age-period-cohort models of the Lee-Carter type

open access: yes, 2016
The predominant way of modelling mortality rates is the Lee-Carter model and its many extensions. The Lee-Carter model and its many extensions use a latent process to forecast.
Beutner, Eric   +2 more
core   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

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