Results 21 to 30 of about 87,864 (261)
Ion channels and calcium signaling in motile cilia
eLife, 2015 The beating of motile cilia generates fluid flow over epithelia in brain ventricles, airways, and Fallopian tubes. Here, we patch clamp single motile cilia of mammalian ependymal cells and examine their potential function as a calcium signaling compartment.
Markus Delling +5 more
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Rsph4a is essential for the triplet radial spoke head assembly of the mouse motile cilia. [PDF]
PLoS Genet, 2020 Motile cilia/flagella are essential for swimming and generating extracellular fluid flow in eukaryotes. Motile cilia harbor a 9+2 arrangement consisting of nine doublet microtubules with dynein arms at the periphery and a pair of singlet microtubules at ...
Yoke H +7 more
europepmc +3 more sources
Cilia density and flow velocity affect alignment of motile cilia from brain cells.
J Exp Biol, 2020 In many organs, thousands of microscopic ‘motile cilia’ beat in a coordinated fashion generating fluid flow. Physiologically, these flows are important in both development and homeostasis of ciliated tissues.
Pellicciotta N +6 more
europepmc +4 more sources
Emergence of Collective Dynamics in Systems of Motile Cilia [PDF]
Biophysical Journal, 2014 Motile cilia are fascinating structures, evolved very early in eukaryotes, and highly conserved throughout organisms of very different complexity. They generate the transport of fluid by periodic beating, through remarkably organized behaviour in space and time (e.g. collective waves).
Stephen D. Simpson +7 more
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Cyclic GMP and Cilia Motility [PDF]
Cells, 2015 Motile cilia of the lungs respond to environmental challenges by increasing their ciliary beat frequency in order to enhance mucociliary clearance as a fundamental tenant of innate defense. One important second messenger in transducing the regulable nature of motile cilia is cyclic guanosine 3′,5′-monophosphate (cGMP).
Todd A. Wyatt
openaire +5 more sources
Computational Modeling of Motile Cilia-Driven Cerebrospinal Flow in the Brain Ventricles of Zebrafish Embryo. [PDF]
Bioengineering (Basel), 2022 Motile cilia are hair-like microscopic structures which generate directional flow to provide fluid transport in various biological processes. Ciliary beating is one of the sources of cerebrospinal flow (CSF) in brain ventricles.
Salman HE, Jurisch-Yaksi N, Yalcin HC.
europepmc +4 more sources
eLife, 2017 Foxj1a is necessary and sufficient to specify motile cilia. Using transcriptional studies and slow-scan two-photon live imaging capable of identifying the number of motile and immotile cilia, we now established that the final number of motile cilia ...
Barbara Tavares +12 more
doaj +2 more sources
Redox regulation of motile cilia in airway disease. [PDF]
Redox Biol, 2019 Motile cilia on airway cells are necessary for clearance of mucus-trapped particles out of the lung. Ciliated airway epithelial cells are uniquely exposed to oxidants through trapping of particles, debris and pathogens in mucus and the direct exposure to inhaled oxidant gases.
Price ME, Sisson JH.
europepmc +5 more sources
Axoneme Structure from Motile Cilia [PDF]
Cold Spring Harbor Perspectives in Biology, 2016 The axoneme is the main extracellular part of cilia and flagella in eukaryotes. It consists of a microtubule cytoskeleton, which normally comprises nine doublets. In motile cilia, dynein ATPase motor proteins generate sliding motions between adjacent microtubules, which are integrated into a well-orchestrated beating or rotational motion.
T. Ishikawa
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Control of synchronization in models of hydrodynamically coupled motile cilia
Communications Physics, 2018 In many organisms, multiple motile cilia coordinate their beating to facilitate swimming or driving of surface flows. Simple models are required to gain a quantitative understanding of how such coordination is achieved; there are two scales of phenomena,
Armando Maestro +5 more
openalex +2 more sources