Results 1 to 10 of about 722,567 (342)

Loss of Motor Protein MYO1C Causes Rhodopsin Mislocalization and Results in Impaired Visual Function [PDF]

open access: yesCells, 2021
Unconventional myosins, linked to deafness, are also proposed to play a role in retinal cell physiology. However, their direct role in photoreceptor function remains unclear.
Ashish K. Solanki   +11 more
doaj   +2 more sources

Structures of kinesin motor proteins [PDF]

open access: bronzeCell Motility, 2009
AbstractAlmost 25 years of kinesin research have led to the accumulation of a large body of knowledge about this widespread superfamily of motor and nonmotor proteins present in all eukaryotic cells. This review covers developments in kinesin research with an emphasis on structural aspects obtained by X‐ray crystallography and cryoelectron microscopy 3‐
Marx, A., Hoenger, A., Mandelkow, E.
openaire   +4 more sources

Reactive Astrocytes Promote ALS-like Degeneration and Intracellular Protein Aggregation in Human Motor Neurons by Disrupting Autophagy through TGF-β1 [PDF]

open access: goldStem Cell Reports, 2017
Summary: Amyotrophic lateral sclerosis (ALS) is a fatal and rapidly progressing motor neuron disease. Astrocytic factors are known to contribute to motor neuron degeneration and death in ALS.
Pratibha Tripathi   +12 more
doaj   +2 more sources

Temporal Patterns of Angular Displacement of Endosomes: Insights into Motor Protein Exchange Dynamics [PDF]

open access: yesAdvanced Science
The material transport system, facilitated by motor proteins, plays a vital role in maintaining a non‐equilibrium cellular state. However, understanding the temporal coordination of motor protein activity requires an advanced imaging technique capable of
Siwoo Jin   +6 more
doaj   +2 more sources

Agl, the multitasking motor protein. [PDF]

open access: yesPLoS Biology, 2013
​ItIt slices, it dices, it cleans the kitchen sink. We've all heard of—and hailed the ingenious efficiency of—devices that perform more than one function. But humans don't have the corner on that market. A team led by Tâm Mignot and Morgane Wartel recently discovered that when the going gets rough, a common soil-inhabiting bacterium, Myxococcus xanthus,
Mary Hoff
doaj   +4 more sources

The crowding dynamics of the motor protein kinesin-II. [PDF]

open access: yesPLoS ONE, 2020
Intraflagellar transport (IFT) in C. elegans chemosensory cilia is an example of functional coordination and cooperation of two motor proteins with distinct motility properties operating together in large groups to transport cargoes: a fast and ...
Vandana S Kushwaha   +5 more
doaj   +2 more sources

Gliding Assay to Analyze Microtubule-based Motor Protein Dynamics [PDF]

open access: yesBio-Protocol, 2017
The purpose of this protocol is to provide an updated method of performing microtubule gliding assays and visualizing it using fluorescence microscopy.
Albert Shim   +3 more
doaj   +2 more sources

The thermal dependence and molecular basis of physiological color change in Takydromus septentrionalis (Lacertidae)

open access: yesBiology Open, 2021
One of the main functions of physiological color change is thermoregulation. This change occurs much more rapidly than morphological color change, but the underlying mechanism remains poorly understood.
Kun Guo   +5 more
doaj   +1 more source

Unconventional Myosins from Caenorhabditis elegans as a Probe to Study Human Orthologues

open access: yesBiomolecules, 2022
Unconventional myosins are a superfamily of actin-based motor proteins that perform a number of roles in fundamental cellular processes, including (but not limited to) intracellular trafficking, cell motility, endocytosis, exocytosis and cytokinesis.
Chloe A Johnson   +2 more
doaj   +1 more source

Motor Proteins [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2018
Myosin motors power movements on actin filaments, whereas dynein and kinesin motors power movements on microtubules. The mechanisms of these motor proteins differ, but, in all cases, ATP hydrolysis and subsequent release of the hydrolysis products drives a cycle of interactions with the track (either an actin filament or a microtubule), resulting in ...
H Lee, Sweeney, Erika L F, Holzbaur
openaire   +2 more sources

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