Results 161 to 170 of about 701,388 (349)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Multiple classes and isoforms of the RNA polymerase recycling motor protein HelD. [PDF]

Microbiologyopen, 2021
Larsen JS, Miller M, Oakley AJ, Dixon NE, Lewis PJ.   +4 more
europepmc   +1 more source

Immunocytochemical Localization of the α-, βI-, βII- and γ-subspecies of Protein Kinase C in Monkey Motor Cortex.

, 1991
Shogo Tominaga, Takeshi Tsuiino, Takao Oishi, Naoaki Saito, Kisou Kubota, Chikako Tanaka   +5 more
openalex   +1 more source

Visualization of Cranial Motor Neurons in Live Transgenic Zebrafish Expressing Green Fluorescent Protein Under the Control of theIslet-1Promoter/Enhancer [PDF]

, 2000
Shin‐ichi Higashijima, Yoshiki Hotta, Hitoshi Okamoto   +2 more
openalex   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Human HELB is a processive motor protein that catalyzes RPA clearance from single-stranded DNA. [PDF]

Proc Natl Acad Sci U S A, 2022
Hormeno S, Wilkinson OJ, Aicart-Ramos C, Kuppa S, Antony E, Dillingham MS, Moreno-Herrero F.   +6 more
europepmc   +1 more source

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

Molecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva, Bernardo Orr, Ana Azeredo, Andreia Brandão, Manuel R. Teixeira, Paula Paulo   +5 more
wiley   +1 more source

Editorial: Mechanics of Cell Division

Frontiers in Cell and Developmental Biology, 2020
Yuta Shimamoto, Yuta Shimamoto, Stefanie Redemann, Stefanie Redemann, Daniel Needleman, Daniel Needleman   +5 more
doaj   +1 more source

The flagellar motor protein FliL forms a scaffold of circumferentially positioned rings required for stator activation. [PDF]

Proc Natl Acad Sci U S A, 2022
Tachiyama S, Chan KL, Liu X, Hathroubi S, Peterson B, Khan MF, Ottemann KM, Liu J, Roujeinikova A.   +8 more
europepmc   +1 more source

Role of heat shock protein Hsp25 in the response of the orofacial nuclei motor system to physiological stress

, 1998
Alexander K. Murashov, Sheeva Talebian, Debra J. Wolgemuth   +2 more
openalex   +1 more source