Results 141 to 150 of about 717,772 (297)
Yeast Kinesin-5 Motor Protein CIN8 Promotes Accurate Chromosome Segregation. [PDF]
Cells, 2022 Sherwin D, Huetteman A, Wang Y.
europepmc +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Editorial: Mechanics of Cell Division
Frontiers in Cell and Developmental Biology, 2020 Yuta Shimamoto +5 more
doaj +1 more source
A mechanochemical model of the forward/backward movement of motor protein kinesin-1. [PDF]
J Biol Chem, 2022 Shen B, Zhang Y.
europepmc +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Kinesin-13, a Motor Protein, is Regulated by Polo-like Kinase in Giardia lamblia. [PDF]
Korean J Parasitol, 2022 Park EA, Kim J, Shin MY, Park SJ.
europepmc +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
FtsK, a DNA Motor Protein, Coordinates the Genome Segregation and Early Cell Division Processes in Deinococcus radiodurans. [PDF]
mBio, 2022 Mishra S, Misra HS, Kota S.
europepmc +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Multiple classes and isoforms of the RNA polymerase recycling motor protein HelD. [PDF]
Microbiologyopen, 2021 Larsen JS +4 more
europepmc +1 more source