Results 11 to 20 of about 701,388 (349)
KLC4 shapes axon arbors during development and mediates adult behavior
eLife, 2022 Development of elaborate and polarized neuronal morphology requires precisely regulated transport of cellular cargos by motor proteins such as kinesin-1. Kinesin-1 has numerous cellular cargos which must be delivered to unique neuronal compartments.
Elizabeth M Haynes +7 more
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eLife, 2020 Kinesin-5 motors organize mitotic spindles by sliding apart microtubules. They are homotetramers with dimeric motor and tail domains at both ends of a bipolar minifilament.
Tatyana Bodrug +17 more
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Analysis of membrane structure of the inner ear motor protein prestin by force spectroscopy
Journal of Biomechanical Science and Engineering, 2021 The high sensitivity of mammalian hearing is achieved by cochlear amplification. The basis of this amplification is the motility of outer hair cells (OHCs), which are sensory cells in the inner ear.
Michio MURAKOSHI, Hiroshi WADA
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Structures of kinesin motor proteins [PDF]
Cell Motility, 2009 AbstractAlmost 25 years of kinesin research have led to the accumulation of a large body of knowledge about this widespread superfamily of motor and nonmotor proteins present in all eukaryotic cells. This review covers developments in kinesin research with an emphasis on structural aspects obtained by X‐ray crystallography and cryoelectron microscopy 3‐
Marx, A., Hoenger, A., Mandelkow, E.
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Myosin V executes steps of variable length via structurally constrained diffusion
eLife, 2020 The molecular motor myosin V transports cargo by stepping on actin filaments, executing a random diffusive search for actin binding sites at each step.
David Hathcock +3 more
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Motor Proteins: Myosin Mechanosensors [PDF]
Current Biology, 2008 Mechanosensation is emerging as a general principle of myosin motors. As demonstrated in a recent study, the single-headed myosin I molecule is an exquisite mechanosensor, able to sense strain over a very small force range.
Douglas N. Robinson, Yee Seir Kee
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Coupling of Two Motor Proteins: a New Motor Can Move Faster [PDF]
, 2005 We study the effect of a coupling between two motor domains in highly-processive motor protein complexes. A simple stochastic discrete model, in which the two parts of the protein molecule interact through some energy potential, is presented.
Anatoly B. Kolomeisky +8 more
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The motors of protein import into chloroplasts [PDF]
Plant Signaling & Behavior, 2011 Chloroplast function is largely dependent on its resident proteins, most of which are encoded by the nuclear genome and are synthesized in cytosol. Almost all of these are imported through the translocons located in the outer and inner chloroplast envelope membranes. The motor protein that provides the driving force for protein import has been proposed
Shi, Lan-Xin, Theg, Steven M
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Length control of microtubules by depolymerizing motor proteins [PDF]
, 2008 In many intracellular processes, the length distribution of microtubules is controlled by depolymerizing motor proteins. Experiments have shown that, following non-specific binding to the surface of a microtubule, depolymerizers are transported to the ...
B. S. Govindan +3 more
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Restoration of SMN in Schwann cells reverses myelination defects and improves neuromuscular function in spinal muscular atrophy [PDF]
, 2016 Spinal muscular atrophy (SMA) is a neuromuscular disease caused by low levels of SMN protein, primarily affecting lower motor neurons. Recent evidence from SMA and related conditions suggests that glial cells can influence disease severity.
Brophy, Peter J. +9 more
core +7 more sources