Results 71 to 80 of about 830,352 (306)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, Volume 20, Issue 6, Page 1535-1555, June 2026.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

New Perspectives for Spinal Cord Stimulation in Parkinson’s Disease-Associated Gait Impairment: A Systematic Review

Biomedicines
Parkinson’s Disease is a neurodegenerative disorder manifesting itself as a hypokinetic movement impairment with postural instability and gait disturbance.
Christian G. Seufert, Matthias C. Borutta, Martin Regensburger, Yining Zhao, Thomas Kinfe   +4 more
doaj   +1 more source

A Review of the Relationship Between Vitamin D and Parkinson Disease Symptoms

Frontiers in Neurology, 2020
Vitamin D is a fat-soluble secosteroid that exerts its effects by binding to the vitamin D receptor (VDR), through which it directly and indirectly modulates the expression of hundreds to thousands of genes.
Michelle E. Fullard, John E. Duda, John E. Duda   +2 more
doaj   +1 more source

The psychological impact of motor vehicle accidents : a New Zealand study : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Psychology at Massey University [PDF]

, 1997
PLEASE NOTE Pages 72-73 are missing from the original copyThe present research attempted to identify those factors which predispose victims of severe motor vehicle accidents to develop PTSD, and explored the relationship between mental health and health ...
Kennedy-Moffat, James
core  

Effects of intracerebral neurotrophic factor application on motor symptoms in Parkinson's disease: a systematic review and meta-analysis [PDF]

, 2017
Introduction: Neurotrophic factors (NTFs) have been evaluated for neuroprotective effects in Parkinson's disease (PD). However, clinical trials examining the efficacy of intracerebral administration of NTFs on motor symptoms in PD have produced mixed ...
Hegarty, Shane V., Lee, David J., O'Keeffe, Gerard W., Sullivan, Aideen M.   +3 more
core   +1 more source

Motor Symptoms as a Prodrome to Schizophrenia

Marshall Journal of Medicine, 2022
Schizophrenia occurs in 1% of the population and is severely impairing to those afflicted. Thereby, it is of the utmost importance to recognize and treat the disorder as early as possible. For the last several decades research has attempted to elucidate a variety of predictive factors in order to aid in the identification of patients at high risk of ...
Adam Schindzielorz, Hunter Edwards, Kelly Melvin   +2 more
openaire   +3 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, Volume 20, Issue 6, Page 1494-1512, June 2026.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Prevalence and impact of rapid eye movement sleep behavior disorder in multiple system atrophy: a systematic review and meta-analysis

Frontiers in Neurology
ObjectiveMultiple system atrophy (MSA) is commonly associated with rapid eye movement sleep behavior disorder (RBD). Research on the prevalence of RBD in MSA and its effects on MSA patients has yielded inconsistent results.
Hui Wang, Ting Zhang, Wenhui Fan
doaj   +1 more source

Progression of motor subtypes in Huntington’s disease. a 6-year follow-up study [PDF]

, 2016
The objective of this study is to investigate the progression of predominantly choreatic and hypokinetic-rigid signs in Huntington's disease (HD) and their relationship with cognitive and general functioning over time.
Bentivoglio, A. R., Burgunder, J. M., Craufurd, D., Ferraldeschi, Michela, Hart, E. P., Jacobs, M, Reilmann, R., Ristori, Giovanni, Romano, Silvia, Roos, R. A. C., Saft, C., The REGISTRY, investigators of the European Huntington’s Disease Network, van Zwet, E. W.   +12 more
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, Volume 20, Issue 6, Page 1473-1493, June 2026.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source