Results 1 to 10 of about 4,061,393 (306)

Author Correction: Study of mouse behavior in different gravity environments

open access: yesScientific Reports, 2021
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Michihiko Shimomura   +7 more
doaj   +1 more source

Study of mouse behavior in different gravity environments

open access: yesScientific Reports, 2021
Many experiments have analyzed the effect of the space environment on various organisms. However, except for the group-rearing of mice in space, there has been little information on the behavior of organisms in response to gravity changes. In this study,
Michihiko Shimomura   +7 more
doaj   +1 more source

Exposure to maternal high-fat diet induces extensive changes in the brain of adult offspring

open access: yesTranslational Psychiatry, 2021
Maternal environmental exposures, such as high-fat diets, diabetes and obesity, can induce long-term effects in offspring. These effects include increased risk of neurodevelopmental disorders (NDDs) including autism spectrum disorder (ASD), depression ...
Darren J. Fernandes   +7 more
doaj   +1 more source

Spreading Senescent Cells’ Burden and Emerging Therapeutic Targets for Frailty

open access: yesCells, 2023
The spreading of senescent cells’ burden holds profound implications for frailty, prompting the exploration of novel therapeutic targets. In this perspective review, we delve into the intricate mechanisms underlying senescent cell spreading, its ...
Serena Marcozzi   +6 more
doaj   +1 more source

Retinal cone photoreceptors of the deer mouse Peromyscus maniculatus : development, topography, opsin expression and spectral tuning [PDF]

open access: yes, 2013
A quantitative analysis of photoreceptor properties was performed in the retina of the nocturnal deer mouse, Peromyscus maniculatus, using pigmented (wildtype) and albino animals.
Arbogast, Patrick   +2 more
core   +11 more sources

Novel metabolic role for BDNF in pancreatic β-cell insulin secretion

open access: yesNature Communications, 2020
Glucose metabolism is regulated by hypothalamic brain functions and factors produced by peripheral tissues. Here, the authors show that the regulator of food intake Brain-derived neurotrophic factor is also produced and secreted by muscle and stimulates ...
Gianluca Fulgenzi   +11 more
doaj   +1 more source

Deficiency of protocadherin 9 leads to reduction in positive emotional behaviour

open access: yesScientific Reports, 2022
Protocadherin 9 (Pcdh9) is a member of the cadherin superfamily and is uniquely expressed in the vestibular and limbic systems; however, its physiological role remains unclear.
Masato Uemura   +12 more
doaj   +1 more source

Neuroanatomy in mouse models of Rett syndrome is related to the severity of Mecp2 mutation and behavioral phenotypes

open access: yesMolecular Autism, 2017
Background Rett syndrome (RTT) is a neurodevelopmental disorder that predominantly affects girls. The majority of RTT cases are caused by de novo mutations in methyl-CpG-binding protein 2 (MECP2), and several mouse models have been created to further ...
Rylan Allemang-Grand   +6 more
doaj   +1 more source

Cancer Biology Data Curation at the Mouse Tumor Biology Database (MTB) [PDF]

open access: yes, 2009
Many advances in the field of cancer biology have been made using mouse models of human cancer. The Mouse Tumor Biology (MTB, "http://tumor.informatics.jax.org":http://tumor.informatics.jax.org) database provides web-based access to data on ...
Carol J. Bult   +6 more
core   +2 more sources

BRCA2-DSS1 interaction is dispensable for RAD51 recruitment at replication-induced and meiotic DNA double strand breaks

open access: yesNature Communications, 2022
Mishra et al. have generated mice with a single amino acid substitution in BRCA2, which disrupts its interaction with DSS1 resulting in a severe HR defect. They show the interaction to be dispensable for HR at replication induced and meiotic DSBs.
Arun Prakash Mishra   +15 more
doaj   +1 more source

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