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Author Correction: Study of mouse behavior in different gravity environments
Scientific Reports, 2021 An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Michihiko Shimomura +7 more
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Study of mouse behavior in different gravity environments
Scientific Reports, 2021 Many experiments have analyzed the effect of the space environment on various organisms. However, except for the group-rearing of mice in space, there has been little information on the behavior of organisms in response to gravity changes. In this study,
Michihiko Shimomura +7 more
doaj +1 more source
Exposure to maternal high-fat diet induces extensive changes in the brain of adult offspring
Translational Psychiatry, 2021 Maternal environmental exposures, such as high-fat diets, diabetes and obesity, can induce long-term effects in offspring. These effects include increased risk of neurodevelopmental disorders (NDDs) including autism spectrum disorder (ASD), depression ...
Darren J. Fernandes +7 more
doaj +1 more source
Touchscreen-based cognitive tasks reveal age-related impairment in a primate aging model, the grey mouse lemur (Microcebus murinus) [PDF]
, 2014 Mouse lemurs are suggested to represent promising novel non-human primate models for aging research. However, standardized and cross-taxa cognitive testing methods are still lacking.
Ammersdorfer, Sandra +3 more
core +16 more sources
Spreading Senescent Cells’ Burden and Emerging Therapeutic Targets for Frailty
Cells, 2023 The spreading of senescent cells’ burden holds profound implications for frailty, prompting the exploration of novel therapeutic targets. In this perspective review, we delve into the intricate mechanisms underlying senescent cell spreading, its ...
Serena Marcozzi +6 more
doaj +1 more source
Novel metabolic role for BDNF in pancreatic β-cell insulin secretion
Nature Communications, 2020 Glucose metabolism is regulated by hypothalamic brain functions and factors produced by peripheral tissues. Here, the authors show that the regulator of food intake Brain-derived neurotrophic factor is also produced and secreted by muscle and stimulates ...
Gianluca Fulgenzi +11 more
doaj +1 more source
Deficiency of protocadherin 9 leads to reduction in positive emotional behaviour
Scientific Reports, 2022 Protocadherin 9 (Pcdh9) is a member of the cadherin superfamily and is uniquely expressed in the vestibular and limbic systems; however, its physiological role remains unclear.
Masato Uemura +12 more
doaj +1 more source
Molecular Autism, 2017 Background Rett syndrome (RTT) is a neurodevelopmental disorder that predominantly affects girls. The majority of RTT cases are caused by de novo mutations in methyl-CpG-binding protein 2 (MECP2), and several mouse models have been created to further ...
Rylan Allemang-Grand +6 more
doaj +1 more source
Nature Communications, 2022 Mishra et al. have generated mice with a single amino acid substitution in BRCA2, which disrupts its interaction with DSS1 resulting in a severe HR defect. They show the interaction to be dispensable for HR at replication induced and meiotic DSBs.
Arun Prakash Mishra +15 more
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Inflammation-associated enterotypes, host genotype, cage and inter-individual effects drive gut microbiota variation in common laboratory mice [PDF]
, 2013 Background: Murine models are a crucial component of gut microbiome research. Unfortunately, a multitude of genetic backgrounds and experimental setups, together with inter-individual variation, complicates cross-study comparisons and a global ...
Brinkman, Brigitta +7 more
core +3 more sources