Results 11 to 20 of about 4,518,026 (355)
Journal of Clinical Orthopaedics and Trauma, 2013 Fracture shaft humerus when surgically fixed is known to go into non-union and one of the main reasons of this is implant failure. The causes of implant failure may lie in the fracture personality, faulty implant material or choice, dubious surgical technique & faulty mechanics of fixation.
Hitesh, Lal +2 more
openaire +2 more sources
Breast Cancer Research, 2020 Next-generation sequencing of Sri Lankan families with inherited cancer syndromes resulted in the identification of five BRCA2 variants of unknown clinical significance.
Nirmala Sirisena +7 more
doaj +1 more source
Mouse models of colorectal cancer. [PDF]
, 2011 Colorectal cancer is one of the most common malignancies in the world. Many mouse models have been developed to evaluate features of colorectal cancer in humans. These can be grouped into genetically-engineered, chemically-induced, and inoculated models.
Koeffler, H Phillip +2 more
core +2 more sources
npj Genomic Medicine, 2020 Sequencing-based genetic tests to identify individuals at increased risk of hereditary breast and ovarian cancers have resulted in the identification of more than 40,000 sequence variants of BRCA1 and BRCA2. A majority of these variants are considered to
Kajal Biswas +9 more
doaj +1 more source
Brain Sciences, 2021 Acquisition of detailed anatomical and molecular knowledge from intact biological samples while preserving their native three-dimensional structure is still a challenging issue for imaging studies aiming to unravel a system’s functions. Three-dimensional
Olga Ermakova +12 more
doaj +1 more source
A non-conserved amino acid variant regulates differential signalling between human and mouse CD28 [PDF]
, 2018 CD28 superagonistic antibodies (CD28SAb) can preferentially activate and expand immunosuppressive regulatory T cells (Treg) in mice. However, pre-clinical trials assessing CD28SAbs for the therapy of autoimmune diseases reveal severe systemic ...
Alarcon, Balbino +13 more
core +5 more sources
Cancer Biology Data Curation at the Mouse Tumor Biology Database (MTB) [PDF]
, 2009 Many advances in the field of cancer biology have been made using mouse models of human cancer. The Mouse Tumor Biology (MTB, "http://tumor.informatics.jax.org":http://tumor.informatics.jax.org) database provides web-based access to data on ...
Carol J. Bult +6 more
core +2 more sources
The Journal of the American Association of Gynecologic Laparoscopists, 1999 To develop a technique for performing laparoscopy in the mouse.Controlled animal study (Canadian Task Force classification II-1).University research laboratory.Twenty-eight CD-1 pregnant mice.Eight mice underwent anesthesia only and 20 had anesthesia plus laparoscopy at 5.5 and at 10.5 days' gestation (implantation occurs on day 4.5 and delivery on ...
E, Hirsch +3 more
openaire +2 more sources
Alcoholism: Clinical and Experimental Research, 2008 Background: The development of a relatively simple, noninvasive method for estimating blood ethanol concentrations in mice will be useful in behavioral studies related to alcoholism. This study validated such a method.Methods: The apparatus consists of a body chamber fitted with a head stock through which the mouse head protrudes.
Brett C, Ginsburg +6 more
openaire +2 more sources
BRE/BRCC45 regulates CDC25A stability by recruiting USP7 in response to DNA damage
Nature Communications, 2018 Loss of BRCA2 leads to cancer formation. Here, the authors use an insertional mutagenesis approach and identify a multiprotein complex consisting of BRE, USP7 and CDC25A that can support the survival of BRCA2-deficient cells.
Kajal Biswas +9 more
doaj +1 more source