Results 31 to 40 of about 4,061,393 (306)

Monitoring longitudinal disease progression in a novel murine Kit tumor model using high-field MRI

open access: yesScientific Reports, 2022
Animal models are an indispensable platform used in various research disciplines, enabling, for example, studies of basic biological mechanisms, pathological processes and new therapeutic interventions.
Markus Kraiger   +8 more
doaj   +1 more source

The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation

open access: yesNature Communications, 2021
LSH/HELLS is a chromatin remodeler promoting incorporation of histone variant macroH2A. Here the authors reveal a role for LSH in genome stability, in protecting nascent DNA at stalled forks mediated by macroH2A deposition and RAD51 filament formation.
Xiaoping Xu   +11 more
doaj   +1 more source

Chloride channels regulate differentiation and barrier functions of the mammalian airway. [PDF]

open access: yes, 2020
The conducting airway forms a protective mucosal barrier and is the primary target of airway disorders. The molecular events required for the formation and function of the airway mucosal barrier, as well as the mechanisms by which barrier dysfunction ...
Caplan, Michael J   +14 more
core   +2 more sources

Functional loss of Ccdc151 leads to hydrocephalus in a mouse model of primary ciliary dyskinesia

open access: yesDisease Models & Mechanisms, 2019
Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disorder affecting normal structure and function of motile cilia, phenotypically manifested as chronic respiratory infections, laterality defects and infertility.
Francesco Chiani   +7 more
doaj   +1 more source

The orienting mouse: An input device with attitude [PDF]

open access: yes, 2013
This paper presents a modified computer mouse, the Orienting Mouse, which delivers orientation as an additional dimension of input; when the mouse is moved on a flat surface it reports, in addition to the conventional x, y translation, angular rotation ...
Apperley, Mark, Rogers, Bill
core   +1 more source

Intrusion Detection Using Mouse Dynamics

open access: yes, 2018
Compared to other behavioural biometrics, mouse dynamics is a less explored area. General purpose data sets containing unrestricted mouse usage data are usually not available.
Antal, Margit, Egyed-Zsigmond, Elod
core   +2 more sources

Mast cell clones: a model for the analysis of cellular maturation. [PDF]

open access: yes, 1982
Cloned mouse mast cells resemble, by ultrastructure, immature mast cells observed in vivo. These mast cell clones can be grown in the absence of any other cells, facilitating direct investigations of their biochemistry and function.
Cantor, H   +10 more
core   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

”PENGARUH BERBAGAI DOSIS FILTRAT DAUN COCOR BEBEK \ud (Kalanchoe pinnata L.) TERHADAP PENURUNAN SUHU TUBUH TIKUS \ud PUTIH (Rattus norvegicus) HIPERTERMIA” [PDF]

open access: yes, 2009
Fever is situation of body temperature above normal as effect of make-up of center arrangement of temperature in hipotalamus which in influencing by IL-I.
WIJAYANTI, YUNI
core  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

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